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  1. Nov 13, 2020 · Epidemic Typhus. Epidemic typhus, also called louse-borne typhus, is an uncommon disease caused by a bacteria called Rickettsia prowazekii. Epidemic typhus is spread to people through contact with infected body lice. Though epidemic typhus was responsible for millions of deaths in previous centuries, it is now considered a rare disease.

  2. Aug 8, 2023 · Rickettsia prowazekii is an intracellular, gram-negative coccobacillus. It is an obligate parasite. R. prowazekii belongs to the genus Rickettsia and is the causative agent of epidemic typhus. The genus Rickettsia is composed of gram-negative bacteria. Rickettsiae are the closest known relatives of mitochondria in eukaryotic cells.[1][2][3]

    • Sami M. Akram, Megan Ladd, Kevin C. King
    • 2023/08/08
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  4. Oct 13, 2021 · Diagnosis and identification of this intracellular bacteria are challenging with many available diagnostic modalities suffering from several shortcomings. Detection of antibodies directed against Rickettsia spp. via serological methods remains widely used with a broad range of sensitivity and specificity values reported depending on the assay.

    • Adam G. Stewart, Alexandra G. A. Stewart
    • 2021
  5. Jul 17, 2023 · Rickettsia is a group of vector-borne organisms that cause acute febrile illnesses throughout the world.[1] While the clinical presentation of rickettsial infection is similar, the causative species and epidemiology can vary depending on the region. It is important to recognize both the typical symptoms and the epidemiology of a given region to correctly diagnose and treat these infections ...

    • Jessica Snowden, Megan Ladd, Kevin C. King
    • 2023/07/17
  6. Epidemic typhus is a rickettsial disease. Humans are the natural reservoir for R. prowazekii, which is prevalent worldwide and transmitted by body lice when louse feces are scratched or rubbed into bite or other wounds (or sometimes the mucous membranes of the eyes or mouth). In the United States, humans occasionally contract epidemic typhus ...

  7. Symptoms suggest the diagnosis, and to confirm it, doctors do special tests that use a sample from the rash or blood. Antibiotics are given as soon as doctors suspect one of these infections. Rickettsiae and related (rickettsia-like) bacteria (such as Ehrlichia , Anaplasma , and Coxiella burnetii bacteria) are an unusual type of bacteria that ...

  8. Feb 1, 2019 · low blood pressure (hypotension) eye sensitivity to bright lights. severe muscle pain. The symptoms of endemic typhus last for 10 to 12 days and are very similar to the symptoms of epidemic typhus ...

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