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  1. Jan 24, 2023 · Scarlet Fever: A Deadly History and How it Prevails. Portrait of Dr. Giovanni Ingrassia. Scarlet fever is a disease that has significantly evolved in definition and management over the last several hundred years. The disease, which is caused by a toxin produced by the bacteria Streptococcus pyogenes, was once enormously prevalent amongst the ...

  2. Scarlet fever. Scarlet fever, also known as scarlatina, is an infectious disease caused by Streptococcus pyogenes, a Group A streptococcus (GAS). [3] It most commonly affects children between five and 15 years of age. [1] The signs and symptoms include a sore throat, fever, headache, swollen lymph nodes, and a characteristic rash. [1]

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  4. Apr 1, 2024 · scarlet fever, acute infectious disease caused by group A hemolytic streptococcal bacteria, in particular Streptococcus pyogenes. Scarlet fever can affect people of all ages, but it is most often seen in children. It is called scarlet fever because of the red skin rash that accompanies it. Before the advent of antibiotics, scarlet fever was ...

    • The Editors of Encyclopaedia Britannica
  5. Feb 10, 2016 · According to Rolleston (Rolleston, 1928) in his article on the history of scarlet fever, Giovanni Filippo Ingrassias, a Sicilian anatomist and practitioner, wrote in 1553 (Ingrassia, 1553) the first description of a disease termed “rossalia” that was characterized by “numerous spots, large and small, fiery and red, of universal ...

    • Joseph Ferretti, Werner Köhler
    • 2016
  6. Jan 16, 2023 · Scarlet fever is a rash most commonly associated with bacterial pharyngitis in school-age and adolescent children. It is a blanching, papular rash that is classically described as a “sandpaper” rash. The causative bacteria is Streptococcus pyogenes, which generates an endotoxin mainly responsible for the skin manifestation of the infection.

  7. Signs of scarlet fever rash: Red rash that feels rough like sandpaper. Brighter red skin in the creases of the underarm, elbow, and groin. A pale area around the mouth. Skin peeling as the rash fades. One to 2 days after the illness begins, a red rash usually appears.

  8. Dec 30, 2021 · Abstract. Streptococcus pyogenes (group A Streptococcus) is a globally disseminated and human-adapted bacterial pathogen that causes a wide range of infections, including scarlet fever. Scarlet fever is a toxin-mediated disease characterized by the formation of an erythematous, sandpaper-like rash that typically occurs in children aged 5 to 15.

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