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  1. May 6, 2024 · What are the signs and symptoms of scleroderma? Mild scleroderma may only affect the skin on your fingers, hands, toes, and face. Severe scleroderma may spread to skin on your midsection, or your organs, blood vessels, joints, and muscles. You may have any of the following: Cold or blue fingers and toes, or skin color changes

  2. 6 days ago · Scleroderma can cause swelling of the hands and feet, red spots may appear on the skin (telangiectasias), as well as excessive calcium deposition in the skin (calcinosis) and pain and stiffness of ...

  3. Apr 24, 2024 · Vanessa L. Malcarne. Abstract. Changes in appearance are a common and distressing aspect of scleroderma. Disfigurement in scleroderma often occurs in areas of the body that are both visible and socially relevant (e.g., face and hands), which can contribute to increased social anxiety and avoidance.

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  5. Apr 19, 2024 · The guttata form (also known as the confetti type) of circumscribed scleroderma (morphea guttata) usually shows disseminated, rump accentuated yellowish-whitish, superficially shiny, slightly indurated patches, papules or plaques barely 1 cm in size. Initially, pale red spots may appear.

  6. 5 days ago · Summary Scleroderma is a rare autoimmune disease characterized by excessive collagen production.It can affect only the skin, or both skin and internal organs. It leads to the thickening of connective tissue and potential complications in organs such as the lungs, heart, and kidneys, which can ultimately result in death.Early signs, like excessive vessels constricting (called

  7. Apr 24, 2024 · Morphea, also called localized scleroderma, is a sclerosing skin disorder that resembles scleroderma (systemic sclerosis) in terms of cutaneous histopathological features but differs demographically and clinically. Hallmark clinical and serological features of...

  8. Apr 25, 2024 · The Role of Auto antibodies What is Scleroderma? Scleroderma, derived from the Greek meaning "hard skin", is a complex autoimmune condition marked by fibrosis. It's as if your body suddenly decides to overproduce collagen, turning supple, soft skin into something rigid and hard. Under normal circumstances, our immune system is our body's loyal guardian, fighting

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