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  1. en.wikipedia.org › wiki › Scrub_typhusScrub typhus - Wikipedia

    Scrub typhus or bush typhus is a form of typhus caused by the intracellular parasite Orientia tsutsugamushi, a Gram-negative α-proteobacterium of family Rickettsiaceae first isolated and identified in 1930 in Japan. [2] [3]

  2. Apr 1, 2020 · Historical reference to the rickettsial disease scrub typhus was first described in China (313 AD) by Hong Ge in a clinical manual (Zhouhofang) and in Japan (1810 AD) when Hakuju Hashimoto described tsutsuga, a noxious harmful disease in the Niigata prefecture.

    • Allen L Richards, Ju Jiang
    • 10.3390/tropicalmed5020049
    • 2020
    • Trop Med Infect Dis. 2020 Jun; 5(2): 49.
  3. Jan 17, 2018 · The IFA was developed in 1963 in an indirect IFA format using Karp and Gilliam strains for diagnosis of scrub typhus [ 199 ]. The ability of the assay in typing of scrub typhus using Karp, Kato and Gilliam strains with fluorescent antibody in a direct IFA format was subsequently demonstrated [ 200 ].

    • Alison Luce-Fedrow, Marcie L. Lehman, Daryl J. Kelly, Kristin Mullins, Alice N. Maina, Richard L. St...
    • 10.3390/tropicalmed3010008
    • 2018
    • Trop Med Infect Dis. 2018 Mar; 3(1): 8.
  4. The disease, scrub typhus, occurs when infected mite larvae accidentally bite humans. This infection can prove fatal if prompt doxycycline therapy is not started. Orientia tsutsugamushi infection was first reported in Japan by Hakuju Hashimoto in 1810, and to the Western world by Theobald Adrian Palm in 1878.

  5. Sep 26, 2022 · Go to: Etiology. Scrub typhus in its region of endemicity is one of the causes of acute febrile illness which usually is underdiagnosed. It can affect multiple organ systems principally by its vasculitis and perivascular inflammation.

  6. Nov 13, 2020 · Prevention. Scrub typhus, also known as bush typhus, is a disease caused by a bacteria called Orientia tsutsugamushi. Scrub typhus is spread to people through bites of infected chiggers (larval mites). The most common symptoms of scrub typhus include fever, headache, body aches, and sometimes rash.

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