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  1. Dec 10, 2021 · The Surviving Sepsis Campaign (SSC) is a joint collaboration of the Society of Critical Care Medicine and the European Society of Intensive Care Medicine, which is committed to reducing mortality and morbidity from sepsis and septic shock worldwide.

  2. Jun 6, 2021 · Hospital readmission within 90 days of discharge occurs in approximately 40% of sepsis survivors and is associated with high costs [ 624 ]. In addition, sepsis survivors are at increased risk for recurrent infection, AKI and new cardiovascular events compared to patients hospitalised for other diagnoses [ 580 ].

  3. Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection ( 1 ). Sepsis and septic shock are major healthcare problems, impacting millions of people around the world each year and killing between one in three and one in six of those it affects ( 2–4 ).

  4. Under the new definition, sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, where organ dysfunction is defined as an increase in the Sequential [Sepsis-related] Organ Failure Assessment (SOFA) score of 2 points or more, which is associated with an in-hospital mortality greater than 10%.

  5. Sepsis represents life-threatening organ dysfunction caused by a dysregulated response to infection that kills up to one in three affected people. Early...

  6. Sepsis: Suspected or documented infection and an acute increase of 2 SOFA points (a proxy for organ dysfunction) Septic Shock: Sepsis and vasopressor therapy needed to elevate MAP ≥ 65 mmg Hg and lactate > 2 mmol/L (18 mg/dL) after adequate fluid resuscitation.

  7. Oct 2, 2021 · Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Intensive Care Med. 2021 Nov;47 (11):1181-1247. doi: 10.1007/s00134-021-06506-y. Epub 2021 Oct 2. Authors.

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