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  1. Sickle cell disease (SCD) is a common inherited blood disorder in the United States, affecting an estimated 70,000 to 100,000 Americans. SCD can lead to lifelong disabilities and reduce average life expectancy.

  2. The symptoms of sickle cell disease may look like other blood disorders or medical problems. Always consult your health care provider for a diagnosis. How is sickle cell disease diagnosed? Along with a complete medical history and physical exam, you may have blood and other tests.

  3. Jun 3, 2022 · Overview. What is sickle cell anemia? Sickle cell anemia is a form of the inherited blood disorder, sickle cell disease. Sickle cell anemia affects your red blood cells, turning them from round flexible discs into stiff and sticky sickled cells. Sickled cells keep red blood cells from doing their job, which is carrying oxygen throughout your body.

  4. Apr 22, 2024 · Symptoms can vary depending on the individual, but they may include a yellow skin color (jaundice), tiredness, and painful swelling of the hands and feet. More serious symptoms requiring medical attention include severe anemia, fever, acute chest syndrome, stroke, and priapism (a prolonged erection).

  5. Symptoms |. Diagnosis |. Treatment |. More Information. Sickle cell disease is an inherited genetic abnormality of hemoglobin (the oxygen-carrying protein found in red blood cells) characterized by sickle (crescent)-shaped red blood cells and chronic anemia caused by excessive destruction of the abnormal red blood cells.

  6. Apr 22, 2024 · Symptoms. Last updated on April 22, 2024. Back to top. Sickle cell disease is an inherited blood disorder that affects hemoglobin, the protein that carries oxygen through the body. Misshapen red blood cells can block blood flow causing lifelong health problems.

  7. Print. Sickle cell disease causes “sickle” shaped red blood cells. Sickle cell disease (SCD) is an inherited blood disorder that causes “sickle” shaped red blood cells that can stick together, blocking blood flow and oxygen from reaching all parts of the body.

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