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  1. Doberman pinscher Background Clinical Signs Treatment Laboratory Diagnosis Inheritance & Breeding Recommendations Breed Summaries Background von Willebrand Disease (abbreviated vWD) is an inherited bleeding disorder caused by lack of von Willebrand factor protein (vWF). This protein circulates in the blood stream and must be present at the site of blood vessel injury in order to control ...

  2. Von Willebrand Disease (vWD) is an inherited bleeding disorder that makes it difficult for blood to clot. It is the most common inherited bleeding disorder in dogs, and it can be seen more frequently in certain breeds, such as Doberman Pinschers. Dogs with vWD may show signs of bleeding, such as skin bruising, bleeding from the gums or nose ...

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  4. Apr 9, 2024 · Learn more ». Von Willebrand‘s disease (vWD) in dogs is characterized by a deficiency in particular proteins used to help platelets stick together. This complex of proteins is called the von ...

  5. Mar 13, 2004 · Von Willebrand's factor is a protein complex produced both by platelets (the blood cells involved in clotting) and by the cells lining blood vessels. It is made up of several smaller proteins bound together. Von Willebrand's disease results when there is a defect in any one of these proteins. When a blood vessel tears and bleeding occurs ...

  6. Von Willebrand’s disease (vWB) is a blood disease caused by a deficiency of von Willebrand factor (vWF), an adhesive glycoprotein in the blood required for clotting at the sites of small blood vessel injuries. In addition, vWF is a protein for coagulation Factor VIII, a protein essential for blood to clot.

  7. Mar 11, 2024 · Von Willebrand disease is a bleeding disorder that affects some purebred dogs. It causes problems with how your dog’s blood clots, putting them at risk for unusually heavy bleeding. It's common ...

  8. Most dogs that lack the von Willebrand factor show no symptoms, but in more severe cases, symptoms such as nosebleeds and bloody stools may begin to appear by the time the dog is one year old. Most dogs with mild or moderate vWD often lead a decent quality of life, requiring minimal or no treatment. However, dogs with more severe forms of the ...

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