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Von Willebrand's disease (vWD) is the most common inherited bleeding disorder of both humans and dogs. It is caused by a deficiency in the amount of a specific protein needed to help platelets (the blood cells used in clotting) stick together and form clots to seal broken blood vessels. The deficient protein is called von Willebrand factor (vWF).
Von Willebrand disease is genetic in nature. Its mode of inheritance is autosomal incomplete dominant. Dogs possessing two copies of the mutant gene have the most severe form of the disease. Dogs with only one copy of the mutant gene responsible for Von Willebrand’s disease sometimes show no clinical symptoms.
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Von Willebrand Disease (vWD) is an inherited bleeding disorder that makes it difficult for blood to clot. It is the most common inherited bleeding disorder in dogs, and it can be seen more frequently in certain breeds, such as Doberman Pinschers. Dogs with vWD may show signs of bleeding, such as skin bruising, bleeding from the gums or nose ...
Most dogs that lack the von Willebrand factor show no symptoms, but in more severe cases, symptoms such as nosebleeds and bloody stools may begin to appear by the time the dog is one year old. Most dogs with mild or moderate vWD often lead a decent quality of life, requiring minimal or no treatment. However, dogs with more severe forms of the ...
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Jul 3, 2023 · The disease has three forms (Types 1, 2, and 3). Type 1 von Willebrand’s disease is typically less severe than Types 2 and 3; however, it can still cause serious bleeding problems. Both male and female dogs can develop the disease or be carriers of the genetic mutation. Von Willebrand’s disease is inherited in an autosomal recessive pattern.
Apr 9, 2024 · Learn more ». Von Willebrand‘s disease (vWD) in dogs is characterized by a deficiency in particular proteins used to help platelets stick together. This complex of proteins is called the von ...
Von Willebrand’s disease is a chronic lifelong problem and dogs with this disease will need to be monitored carefully for any signs of bleeding. Dogs with von Willebrand disease are prone to developing hypothyroidism. Annual thyroid tests should be done and daily thyroid medication will be prescribed if the dog develops hypothyroidism.
