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  1. Doberman pinscher Background Clinical Signs Treatment Laboratory Diagnosis Inheritance & Breeding Recommendations Breed Summaries Background von Willebrand Disease (abbreviated vWD) is an inherited bleeding disorder caused by lack of von Willebrand factor protein (vWF). This protein circulates in the blood stream and must be present at the site of blood vessel injury in order to control ...

  2. Most dogs that lack the von Willebrand factor show no symptoms, but in more severe cases, symptoms such as nosebleeds and bloody stools may begin to appear by the time the dog is one year old. Most dogs with mild or moderate vWD often lead a decent quality of life, requiring minimal or no treatment. However, dogs with more severe forms of the ...

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  4. Mar 11, 2024 · There are different types of von Willebrand disease, which have different implications for dogs: Type 1: With Type 1, the most common form, there is an abnormally low amount of von Willebrand ...

    • Rebekah Kuschmider
  5. Von Willebrand’s disease (vWB) is a blood disease caused by a deficiency of von Willebrand factor (vWF), an adhesive glycoprotein in the blood required for clotting at the sites of small blood vessel injuries. In addition, vWF is a protein for coagulation Factor VIII, a protein essential for blood to clot.

  6. Mar 13, 2004 · Von Willebrand's factor is a protein complex produced both by platelets (the blood cells involved in clotting) and by the cells lining blood vessels. It is made up of several smaller proteins bound together. Von Willebrand's disease results when there is a defect in any one of these proteins. When a blood vessel tears and bleeding occurs ...

  7. Apr 9, 2024 · Learn more ». Von Willebrand‘s disease (vWD) in dogs is characterized by a deficiency in particular proteins used to help platelets stick together. This complex of proteins is called the von ...

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