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  1. Mar 11, 2024 · 5 min read. Von Willebrand disease is a bleeding disorder that affects some purebred dogs. It causes problems with how your dog’s blood clots, putting them at risk for unusually heavy...

  2. Learn about the causes, symptoms, and treatment options for Van Willebrand's disease in dogs on vcahospitals.com -- your trusted resource for pet health info.

  3. Dogs with vWD may show signs of bleeding, such as skin bruising, bleeding from the gums or nose, and excessive bleeding during surgery. While there is no cure for vWD, dogs can have a normal lifespan with proper care. Causes. A protein called the von Willebrand Factor (vWF) plays an important role in clot formation.

  4. Mar 13, 2004 · Von Willebrand's factor is a protein complex produced both by platelets (the blood cells involved in clotting) and by the cells lining blood vessels. It is made up of several smaller proteins bound together. Von Willebrand's disease results when there is a defect in any one of these proteins. When a blood vessel tears and bleeding occurs ...

  5. Von Willebrand’s disease (vWB) is a blood disease caused by a deficiency of von Willebrand factor (vWF), an adhesive glycoprotein in the blood required for clotting at the sites of small blood vessel injuries. In addition, vWF is a protein for coagulation Factor VIII, a protein essential for blood to clot.

  6. Von Willebrand disease (vWD) is a common hereditary bleeding disorder characterized by a deficiency of the von Willebrand factor, a protein that’s needed to help the blood clot. Its symptoms can be dormant or difficult to spot and if left untreated, vWD can be life-threatening.

  7. Jul 3, 2023 · Von Willebrands Disease Symptoms. Many dogs with Type 1 vWD never show signs or have very mild bleeding tendencies. Prolonged bleeding after trauma or surgery may be the first time an abnormality is noticed. More severe signs and symptoms of von Willebrands disease in dogs include: Spontaneous bleeding from the nose or gums; Bloody urine ...