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1. www.zoetispetcare.com › products › simparica-trioSimparica Trio for Pet Owners | Zoetis Petcare

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   Simparica Trio is a monthly chewable that prevents heartworm disease, ticks, fleas, and intestinal parasites in dogs. Learn about the benefits, safety, and sources of this product from Zoetis Petcare.

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     Simparica Trio contains sarolaner, a member of the...

   • Reminders

     Simparica Trio contains sarolaner, a member of the...

2. Videos

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     Simparica Trio® - Winning Parasite Protection TV Commercial

     Aug 2, 2023

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     Simparica Trio for Dogs | Flea, Tick & Heartworm Dog Treatment | VetSupply

     May 19, 2023

     1.5K Views

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     1:22

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     Simparica Trio: Multi Parasite Treatment for Dogs

     Apr 4, 2022

     2.1K Views

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3. www.simparicatriodvm.comSimparica Trio | Zoetis Petcare

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   Simparica Trio is a monthly chewable that prevents heartworm disease, ticks, fleas, roundworms and hookworms in dogs. It is the first and only product that combines sarolaner, moxidectin and pyrantel in one simple-to-give chewable.

4. www.chewy.com › brands › simparica-trio-11145Simparica Trio - Free shipping | Chewy

   www.chewy.com › brands › simparica-trio-11145

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   Simparica Trio is a monthly chewable tablet that protects dogs against heartworm disease, ticks, fleas, roundworms and hookworms. Shop by dog weight and get free shipping from Chewy.com, a trusted online pet store.

5. Ads · Simparica trio

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6. www.dailypaws.com › simparica-trio-for-dogs-7492138Simparica Trio for Dogs: Side Effects, Uses, and Safety

   www.dailypaws.com › simparica-trio-for-dogs-7492138

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   Apr 11, 2024 · Simparica Trio costs less per dose when purchased in a 12-pack (compared to the six-pack or individual doses). Although the price may be even lower via online pharmacies, Zoetis only guarantees the product when purchased directly through your vet (in the clinic or via their online pharmacy).

7. www.drugs.com › vet › simparica-trioSimparica TRIO for Dogs - Drugs.com

   www.drugs.com › vet › simparica-trio

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   • Description
   • Simparica Trio Indications
   • Simparica Trio Dosage and Administration
   • Warnings
   • Precautions
   • Adverse Reactions
   • Contact Information
   • Clinical Pharmacology
   • Mode of Action
   • Heartworm Prevention
   • GeneratedCaptionsTabForHeroSec

   SIMPARICA TRIO (sarolaner, moxidectin, and pyrantel chewable tablets) is a flavored, chewable tablet for administration to dogs 8 weeks of age and older. Each tablet is formulated to provide minimum dosages of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 µg/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). Sarolaner is a mem...

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   SIMPARICA TRIO is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina) and hookworm (L4, immature adult, and adult Ancylostoma caninum and adult Uncinaria stenocephala) infections. SIMPARICA TRIO kills adu...

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   SIMPARICA TRIO is given orally once a month, at the recommended minimum dose of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 µg/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). Dosage Schedule SIMPARICA TRIO can be offered to the dog with or without food. Care should be taken to ensure that the dog consumes the complete dos...

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   Not for use in humans. Keep this and all drugs out of reach of children. Keep SIMPARICA TRIO in a secure location out of reach of dogs, cats and other animals to prevent accidental ingestion or overdose.

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   Sarolaner, one of the ingredients in SIMPARICA TRIO, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a histor...

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   In a field safety and effectiveness study, SIMPARICA TRIO was administered to dogs for the prevention of heartworm disease. The study included a total of 410 dogs treated once monthly for 11 treatments (272 treated with SIMPARICA TRIO and 138 treated with an active control). Over the 330-day study period, all observations of potential adverse react...

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   For a copy of the Safety Data Sheet or to report adverse reactions, call Zoetis Inc. at 1-888-963-8471. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or www.fda.gov/reportanimalae.

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   Following oral administration of SIMPARICA TRIO in Beagle dogs (13 to 15 months of age at the time of initial dosing), sarolaner and moxidectin were rapidly and well-absorbed. Following a single oral dose of SIMPARICA TRIO (sarolaner dose of 1.2 mg/kg), the sarolaner mean maximum plasma concentration (Cmax) was 523 ng/mL with a mean time to maximum...

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   SIMPARICA TRIO contains three active pharmaceutical ingredients, sarolaner, moxidectin, and pyrantel pamoate. Sarolaner is an acaricide and insecticide belonging to the isoxazoline group. Sarolaner inhibits the function of the neurotransmitter gamma aminobutyric acid (GABA) receptor and glutamate receptor, and works at the neuromuscular junction in...

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   In two well-controlled laboratory studies, a single oral dose of SIMPARICA TRIO was 100% effective in preventing the development of adult D. immitisin dogs inoculated with infective larvae 30 days before treatment. In a well-controlled US field study consisting of 246 dogs administered SIMPARICA TRIO and 119 administered an active control, no dogs ...

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   Simparica TRIO is a chewable tablet that prevents heartworm disease, treats and controls roundworms, hookworms, fleas and ticks in dogs. Learn about its indications, dosage, warnings and cautions, and company information.

   See full list on drugs.com

   • Customer Service: 888-963-8471
   • Website: www.zoetis.com

   • Telephone: 269-359-4414

8. People also ask

   Is simparica trio safe for dogs?

   • Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs.

   Simparica Trio for Pet Owners | Zoetis Petcare

   www.zoetispetcare.com/products/simparica-trio

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   Does simparica trio kill worms?

   • It contains sarolaner, which kills fleas and ticks, moxidectin, which helps prevent heartworm disease and pyrantel, which treats and controls roundworm and hookworm. Is Simparica Trio good for dogs?

   Simparica Trio Flea & Tick Medicine for Dogs | Petco

   www.petco.com/shop/en/petcostore/brand/simparica-trio

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   How does simparica trio work?

   • Simparica Trio is a once-monthly chewable tablet that can treat existing flea and tick infestations and help prevent fleas, ticks, heartworm, roundworm and hookworm. It contains sarolaner, which kills fleas and ticks, moxidectin, which helps prevent heartworm disease and pyrantel, which treats and controls roundworm and hookworm.

   Simparica Trio Flea & Tick Medicine for Dogs | Petco

   www.petco.com/shop/en/petcostore/brand/simparica-trio

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   Can you get simparica trio over-the-counter?

   • Manufactured by Zoetis, Simparica Trio contains three drugs: sarolaner, moxidectin, and pyrantel pamoate. It's only available with a prescription from your veterinarian, so you cannot get it over-the-counter. Sarolaner is an acaricide (kills ticks and mites) and insecticide (kills fleas) belonging to the isoxazoline class of drugs.

   Simparica Trio for Dogs: Side Effects, Uses, and Safety - Daily Paws

   www.dailypaws.com/simparica-trio-for-dogs-7492138

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9. www.costco.com › cmpp-zoetis-simparica-trioZoetis Simparica Trio Information | Costco

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   Simparica Trio is the first FDA-approved monthly chewable that protects your dog against heartworm disease, ticks, fleas, roundworms, and hookworms. Simparica Trio does the work of two or three parasiticides in a single chewable by combining three proven ingredients. It’s available with a veterinarian prescription and is backed by a 100% ...

10. www.petco.com › en › petcostoreSimparica Trio Flea & Tick Medicine for Dogs | Petco

    www.petco.com › en › petcostore

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    Simparica Trio is a monthly chewable tablet that treats and prevents fleas, ticks, heartworm, roundworm and hookworm in dogs. Shop Petco for different sizes and dosages of Simparica Trio and learn more about its benefits and side effects.