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  2. Apr 7, 2021 · ROSEMONT, Ill. (April 7, 2021) — As COVID-19 vaccination ramps up globally, new research published today in the Journal of the American Academy of Dermatology demonstrates the wide variety of skin rashes, including full-body rashes, observed after COVID-19 vaccination.

    • What Do The Reactions Look like?
    • How Long Does The Reaction Last?
    • How Common Are The Reactions?
    • Why Do The Skin Reactions Happen?
    • What to Do If You Have A Reaction

    The delayed skin reactions described in the reports often resembled the raised, red welts that are caused by an insect sting. However, the reactions' appearances can vary. The JAMA Dermatology report described the reactions as itchy, painful, and swelling pink plaquesat or near the injection site. Kimberly Blumenthal, MD, lead author of the NEJM pa...

    While usually short-lived, these skin reactions can cause significant discomfort and “are likely to generate concerns among patients and requests for evaluation,” the researchers wrote in the NEJM letter, recounting a case in which a reaction was mistaken for the bacterial infection cellulitisand medicated with antibiotics. Antibiotics are medicati...

    The reactions were first observed during a phase 3 clinical trial of the Moderna vaccine. In a study published in the NEJMin February, 2021, the investigators reported that 12,765 (84.2%) of the 15,168 participants who had received the vaccine rather than the placebo developed an immediate skin reaction after receiving their first dose of the vacci...

    Based on the results of skin samples, or biopsies, in both the NEJM and JAMA Dermatology reports the researchers' best guess is that the skin reactions are likely caused by delayed T-cell-mediated hypersensitivity—an intense immune response that begins a minimum of 12 hours after contact with a pathogen or allergen, meaning an infectious or irritat...

    Worry over having a skin reaction should not deter you from getting a COVID-19 vaccine. If you do develop one, don't panic. While it may cause you discomfort, it's likely not serious and should resolve on its own in a short time (about two to 11 days, according to theNEJMstudy). If it worsens after appearing or isn't going away, seek medical care. ...

  3. The majority of current literature regarding cutaneous reactions relate specifically to mRNA COVID-19 vaccinations. The spectrum of reported cutaneous reactions after mRNA vaccination include: Local site reaction. Swelling, erythema, and pain in the vaccinated arm. Median onset of 1 day after vaccination.

  4. Oct 27, 2021 · Recognition that responses to the mRNA Covid-19 vaccines resemble JMR and CBH reactions may lead to skin testing in patients and to other related studies to better understand...

    • Philip W. Askenase
    • 2021
  5. Apr 7, 2021 · USA TODAY. 0:00. 0:49. Getting COVID-19 can cause all manner of odd skin reactions. A new study finds some of them, including COVID toes, a measleslike rash and shingles also can be...

  6. Jun 7, 2021 · The systemic skin reaction varied from maculopapular rashes to papules and patches that were widespread and not simply localised to the vaccine injection site.

  7. May 5, 2021 · A review of 414 skin reactions associated with the Moderna and Pfizer vaccines showed a variety of rashes, eruptions, and injection-site inflammation. Less commonly, patients had episodes of...

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