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EMS professionals should consider sodium nitrite toxicity in patients with a suspected overdose who present with a cyanotic appearance, pulse oximetry that remains around 85% despite oxygen, and dark brown blood seen on venipuncture.
- Matthew R. Neth, Jennifer S. Love, B. Zane Horowitz, Michael D. Shertz, Ritu Sahni, Mohamud R. Daya
- 2021
Mar 17, 2022 · Clinical manifestations of sodium nitrite poisoning include peripheral cyanosis, headache, skin flushing, altered skin color, orthostatic hypotension with reflex tachycardia, hypoxia, altered mental status, nausea, vomiting, diarrhea, loss of consciousness, dysrhythmias, and death. 5
- 10.1002/emp2.12702
- 2022/04
Misuse or excessive use of any medicine or product containing nitrates, whether unintentionally or intentionally, can lead to poisoning. Poisoning can result from swallowing, inhaling, or even skin contact. People have been poisoned after drinking nitrate-contaminated rural well water.
Jul 15, 2023 · First Aid & Emergencies. Reference. Sodium Nitrite Toxicity. Medically Reviewed by Sabrina Felson, MD on July 15, 2023. Written by Alexandra Benisek. What Is Sodium Nitrite Used For? What...
- Overview
- Sodium Nitrate
- Nitric Oxide
- Limits on Sodium Nitrate
This article is about the safety of sodium nitrate, a common preservative used in cured meat products. It explains how nitrates and nitrites serve an important bodily function and are found in vegetables as well as processed meats. The article also discusses the potential dangers of nitrosamines, which can be formed from sodium nitrate, and compare...
Sodium nitrate is a common preservative used in cured meat products, linked to heart disease and diabetes. The human body needs nitrates and nitrites which serve an important bodily function. Most of our nitrates come from vegetables.
85% of the nitrates in our diet come from vegetables, most notably celery, spinach and carrots. These provide the body with healthy carbs and fiber that help prevent conversion of nitrosamines into carcinogens.
The amount of sodium nitrate allowed in cured meat products varies depending on the type of meat but has strict limits set by USDA (e.g., bacon 120 ppm). Celery powder doesn't have these limits as it's not regulated like chemically processed sodium nitrates are by USDA; its residue is about 10 times higher than traditionally cured products'.
Oct 27, 2022 · Sodium nitrite causes increased methemoglobin, resulting in systemic hypoxia, metabolic acidosis, and cyanosis. Since sodium nitrite is a preservative, the ingestion of foods containing an excessive amount of this substance can also cause acute intoxication up to death.
To determine a nitrate dose from a sodium nitrate source, the quantity of sodium nitrate is multiplied by the nitrate proportion (0.73). Thus a nitrate dose from a 5 mg sodium nitrate source is 5x0.73=3.65 mg nitrate.
