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  1. Nitrate poisoning (toxicosis) in animals (especially ruminants) results from excess consumption of nitrates from plants or water or via ingestion of nitrate-containing fertilizers. The nitrate ion (NO) is reduced to nitrite ion (NO), which is rapidly absorbed and leads to the formation of methemoglobin, which inhibits oxygen transport.

    • Larry J. Thompson
  2. The primary purpose of this chapter is to provide public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective on the toxicology of nitrate and nitrite. It contains descriptions and evaluations of toxicological studies and epidemiological investigations and provides conclusions, where possible, on the relevance of toxicity and ...

    • 2017/07
  3. In longterm poisoning, signs include retarded growth, lowered milk production, vitamin A deficiency, reproductive problems, and increased susceptibility to infection. Diagnosis relies on signs and blood tests to measure nitrate and nitrite levels in animals. Field tests for nitrate can also be performed.

    • Larry J. Thompson
  4. This Public Health Statement summarizes the Agency for Toxic Substances and Disease Registry’s (ATSDR) findings on inorganic nitrate and nitrite, including chemical characteristics, exposure risks, possible health effects from exposure, and ways to limit exposure. Nitrate and nitrite can be present in organic or inorganic compounds, depending on their chemical structures. This profile ...

    • 2017/07
  5. By Steve Ensley, DVM, PhD, Veterinary Toxicologist and Mike Carlson, PhD, Analytical Chemist. Nitrate (NO 3) toxicosis is actually caused by nitrite (NO 2 ). Nitrate itself is not toxic, only when it is converted to nitrite. Many species of animals are susceptible to nitrate poisoning, but ruminants are the most commonly affected.

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  7. Oct 27, 2022 · Background: Over the years, forensic pathology has registered the spread of new methods of suicide, such as the ingestion of sodium nitrite. Sodium nitrite causes increased methemoglobin, resulting in systemic hypoxia, metabolic acidosis, and cyanosis. Since sodium nitrite is a preservative, the ingestion of foods containing an excessive amount ...

  8. Nitrate and nitrite are two nitrogen compounds that are needed by plants and animals to live and grow. They occur naturally in soil, water, and air. Nitrate and nitrite are also made in the body. In industry, the majority of nitrate is used as fertilizers for crops or lawns. Nitrate and nitrite are also used in food preservation, some ...

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