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People can become nitrite-poisoned in many different ways. Misuse or excessive use of any medicine or product containing nitrates, whether unintentionally or intentionally, can lead to poisoning. Poisoning can result from swallowing, inhaling, or even skin contact. People have been poisoned after drinking nitrate-contaminated rural well water.
Sodium nitrite is used as a coloring agent or preservative in food, as well as an antimicrobial agent in meat and fish and some cheeses. In high amounts it can be toxic for humans, causing methemoglobinemia. This is an unusual and potentially fatal condition in which hemoglobin is oxidized to methemoglobin (MHb), reducing the amount of oxygen ...
Feb 23, 2024 · Sodium nitrate (and its cousin additive sodium nitrite) is a common preservative used in cured meat products including bacon, deli meat, and jerky. ... but in excess can lead to toxicity. Getting ...
Nov 5, 2020 · EMS professionals should consider sodium nitrite toxicity in patients with a suspected overdose who present with a cyanotic appearance, pulse oximetry that remains around 85% despite oxygen, and dark brown blood seen on venipuncture. Early prehospital contact with the Poison Control Center and ED prenotification in poisoned patients is encouraged.
Describe treatment modalities in the management of methemoglobinemia caused by nitrate and nitrite toxicity. Introduction General principles of supportive care, with attention to removal of the cause, will suffice for most identified cases of methemoglobinemia resulting from nitrates and nitrites.
Mar 25, 2022 · Of the ten deaths attributed to sodium nitrite toxicity, eight were male, and two were female. The age range of decedents was 22–74 years (mean 51.9, SD 21.1), 22–74 years for males (mean 58.4, SD 18.2) and 23–29 years for females (mean 26.0, SD 4.2). Males (80%) and those with a history of depression and/or suicidal ideation (70%) were ...
This Public Health Statement summarizes the Agency for Toxic Substances and Disease Registry’s (ATSDR) findings on inorganic nitrate and nitrite, including chemical characteristics, exposure risks, possible health effects from exposure, and ways to limit exposure. Nitrate and nitrite can be present in organic or inorganic compounds, depending on their chemical structures. This profile ...
