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    • Normal Outward Behavior. Alzheimer’s disease usually starts silently, with brain changes that begin years before anyone notices a problem. When your loved one is in this early phase, they won't have any symptoms that you can spot.
    • Very Mild Changes. You still might not notice anything amiss in your loved one's behavior, but they may be picking up on small differences, things that even a doctor doesn't catch.
    • Mild Decline. It's at this point that you start to notice changes in your loved one's thinking and reasoning, such as: Forgets something they just read.
    • Moderate Decline. During this period, the problems in thinking and reasoning that you noticed in stage 3 get more obvious, and new issues appear.
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    At any age, persons may potentially be free of objective or subjective symptoms of cognition and functional decline and also free of associated behavioral and mood changes. We call these mentally healthy persons at any age, stage 1, or normal.

    Half or more of the population of persons over the age of 65 experience subjective complaints of cognitive and or functional difficulties. The nature of these subjective complaints is characteristic. Elderly persons with these symptoms believe they can no longer recall names as well as they could 5 or 10 years previously. They also frequently devel...

    Various terms have been suggested for this condition, but normal aged forgetfulness is probably the most satisfactory terminology. These symptoms which, by definition, are not notable to intimates or other external observers of the person with normal aged forgetfulness, are generally benign. However, there is some recent evidence that persons with ...

    The dominant mood at this stage is frequently what psychiatrists term a flattening of affect and withdrawal. In other words, the patient often seems less emotionally responsive than previously. This absence of emotional responsivity is probably intimately related to the patients denial of their deficit, which is often also notable at this stage. Al...

    In the absence of complicating medical pathology, the diagnosis of AD can be made with considerable certainty from the beginning of this stage; Studies indicate that the duration of this stage of mild AD is a mean of approximately two years.

    Cognitively, persons at this stage frequently cannot recall such major events and aspects of their current lives as the name of the current president, the weather conditions of the day, or their correct current address. Characteristically, some of these important aspects of current life are recalled, but not others. Also, the information is loosely...

    Remote memory also suffers to the extent that persons may not recall the names of some of the schools which they attended for many years, and from which they graduated. Orientation may be compromised to the extent that the correct year may not be recalled. Calculation deficits are of such magnitude that an educated person has difficulty counting ba...

    For example, patients may put their street clothes on over their night clothes. At approximately the same point in the evolution of AD, but generally, just a little later in the temporal sequence, patients lose the ability to bathe independently without assistance (stage 6b). Characteristically, the earliest and most common deficit in bathing is di...

    Requires assistance adjusting the temperature of the bath water. At approximately the same time as Alzheimers patients begin to lose the ability to put on their clothing properly without assistance, but generally, just a little bit later in the disease course, patients start to require assistance in handling the mechanics of bathing (Figure 7). Dif...

    Requires assistance to maintain continence (Figure 9). People with Alzheimers lose the ability to dress, bathe and toilet without assistance, they develop incontinence. Generally, urinary incontinence precedes fecal incontinence. Strategies to prevent episodes of incontinence include taking the patient to the restroom and supervision of toileting.

    Recall of current events is generally deficient to the extent that the patient cannot name the current national head of state or other, similarly prominent newsworthy figures. Persons at this sixth stage will most often not be able to recall the names of any of the schools which they attended. They may, or may not, recall such basic life events as ...

    In many patients, this rigidity appears to be a precursor to the appearance of overt physical deformities in the form of contractures. Contractures are irreversible deformities which prevent the passive or active range of motion of joints (Figure 14). In the early seventh stage (7a and 7b), approximately 40% of AD patients manifest these deformitie...

    Sucking reflex (Figure 15). Primitive reflexes, also known as infantile reflexes or developmental reflexes, such as the sucking reflex, are evident in stage 7 of people with Alzheimers.

    Babinski or plantar extensor reflex (Figure 16). Another infantile reflex seen in stage 7 Alzheimers patient is the Babinski reflex. This abnormal response to stimulation of the sole of the foot is marked by dorsiflexion of the great toe and fanning of the other digits of the foot.

    Learn about the seven stages of Alzheimer’s disease, from normal to severe, based on the Global Deterioration Scale. Stage 6 is moderate dementia, where the person needs assistance with basic activities of daily life and may have mood changes.

  2. Apr 29, 2024 · Learn about the 3-stage and 7-stage models of Alzheimer’s disease, which describe the symptoms and duration of each stage. Stage 6 is middle dementia, where people lose awareness of present and past events and need assistance with daily living.

  3. Jan 26, 2023 · Dementia is usually considered as having three stages: mild (or “early”), moderate (or “middle”), and severe (or “late”). A more specific stage of dementia is commonly assigned based on symptoms. It can also be helpful to know how symptoms change over stages.

  4. Learn how Alzheimer's disease progresses in three stages: mild, moderate and severe. Find out the common symptoms, challenges and tips for each stage and get resources for caregivers and support.

  5. Stages of Alzheimer disease. The stages of Alzheimer disease usually follow a progressive pattern. But each person moves through the disease stages in his or her own way. Knowing these stages helps healthcare providers and family members make decisions about how to care for someone who has Alzheimer disease.

  6. Mar 28, 2024 · Assistance with personal care, from daily tasks to hygiene, is necessary at this stage. People with stage 6 Alzheimer’s disease may also start to sleep more during the day and wander at night.

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