Mar 27, 2020 · Stages of dengue fever Stage I: The acute fever stage is within day 1 to day 5. The patient at this phase has a high fever (39-40 degrees celsius) with abdominal pain, nausea, vomiting.
Nov 30, 2012 · Melissant CF, Kauffmann RH (1992) Infection with Dengue virus. Neth J Med 41: 272–274. View Article Google Scholar 43. Patey O, Ollivaud L, Breuil J, Lafaix C (1993) Unusual neurologic manifestations occurring during dengue fever infection. Am J Trop Med Hyg 48: 793–802. View Article
- Miranda Chan, Michael A. Johansson
- Risk Factors
Dengue (DENG-gey) fever is a mosquito-borne disease that occurs in tropical and subtropical areas of the world. Mild dengue fever causes a high fever, rash, and muscle and joint pain. A severe form of dengue fever, also called dengue hemorrhagic fever, can cause severe bleeding, a sudden drop in blood pressure (shock) and death.Millions of cases of dengue infection occur worldwide each year. Dengue fever is most common in Southeast Asia and the western Pacific islands, but the disease has bee...
Many people, especially children and teens, may experience no signs or symptoms during a mild case of dengue fever. When symptoms do occur, they usually begin four to seven days after you are bitten by an infected mosquito.Dengue fever causes a high fever — 104 F degrees — and at least two of the following symptoms: 1. Headache 2. Muscle, bone and joint pain 3. Nausea 4. Vomiting 5. Pain behind the eyes 6. Swollen glands 7. RashMost people recover within a week or so. In some cases, symptoms...
Dengue fever is caused by any one of four types of dengue viruses spread by mosquitoes that thrive in and near human lodgings. When a mosquito bites a person infected with a dengue virus, the virus enters the mosquito. When the infected mosquito then bites another person, the virus enters that person's bloodstream.After you've recovered from dengue fever, you have immunity to the type of virus that infected you — but not to the other three dengue fever virus types. The risk of developing seve...
Factors that put you at greater risk of developing dengue fever or a more severe form of the disease include: 1. Living or traveling in tropical areas. Being in tropical and subtropical areas increases your risk of exposure to the virus that causes dengue fever. Especially high-risk areas are Southeast Asia, the western Pacific islands, Latin America and the Caribbean. 2. Prior infection with a dengue fever virus. Previous infection with a dengue fever virus increases your risk of having seve...
If severe, dengue fever can damage the lungs, liver or heart. Blood pressure can drop to dangerous levels, causing shock and, in some cases, death.
One dengue fever vaccine, Dengvaxia, is currently approved for use in those ages 9 to 45 who live in areas with a high incidence of dengue fever. The vaccine is given in three doses over the course of 12 months. Dengvaxia prevents dengue infections slightly more than half the time.The vaccine is approved only for older children because younger vaccinated children appear to be at increased risk of severe dengue fever and hospitalization two years after receiving the vaccine.The World Health Or...
The outlook for dengue hemorrhagic fever depends on how early the condition is detected. People who receive care in the early stages of dengue infection will often recover — according to the ...
Symptoms of dengue can become severe within a few hours. Severe dengue is a medical emergency. Severe dengue. About 1 in 20 people who get sick with dengue will develop severe dengue. Severe dengue can result in shock, internal bleeding, and even death. If you have had dengue in the past, you are more likely to develop severe dengue.
An estimated 1 in 4 dengue virus infections are symptomatic.Symptomatic dengue virus infection most commonly presents as a mild to moderate, nonspecific, acute febrile illness.Approximately 1 in 20 patients with dengue virus disease progress to develop severe, life-threatening disease called severe dengue.Early clinical findings are nonspecific but require a high index of suspicion because recognizing early signs of shock and promptly initiating intensive supportive therapy can reduce risk of death...Fever typically lasts 2–7 days and can be biphasic.Other signs and symptoms may include severe headache; retro-orbital eye pain; muscle, joint, and bone pain; macular or maculopapular rash; and minor hemorrhagic manifestations including petechia, e...Some patients have injected oropharynx and facial erythema in the first 24–48 hours after onset.
- Key Facts
- Febrile Phase
- Warning Signs
- Critical Phase
- Convalescent Phase
- Dengue During Pregnancy
Warning signs of progression to severe dengue occur in the late febrile phase around the time of defervescence, and include persistent vomiting, severe abdominal pain, fluid accumulation, mucosal bleeding, difficulty breathing, lethargy/restlessness, postural hypotension, liver enlargement, and progressive increase in hematocrit (i.e., hemoconcentration).The critical phase of dengue begins at defervescence and typically lasts 24–48 hours.Most patients clinically improve during this phase, but those with substantial plasma leakage can, within a few hours, develop severe dengue as a result of a marked increase in vascular permeability.Initially, physiologic compensatory mechanisms maintain adequate circulation, which narrows pulse pressure as diastolic blood pressure increases.Patients with severe plasma leakage may have pleural effusions, ascites, hypoproteinemia, or hemoconcentration.As plasma leakage subsides, the patient enters the convalescent phase and begins to reabsorb extravasated intravenous fluids and pleural and abdominal effusions.As a patient’s well-being improves, hemodynamic status stabilizes (although he or she may manifest bradycardia), and diuresis ensues. The patient’s hematocrit stabilizes or may fall because of the...The convalescent-phase rash may desquamate and be pruritic.Data are limited on health outcomes of dengue in pregnancy and effects of maternal infection on the developing fetus.Perinatal transmission can occur, and peripartum maternal infection may increase the likelihood of symptomatic infection in the newborn.Of 41 perinatal transmission cases described in the literature, all developed thrombocytopenia, most had evidence of plasma leakage evidenced by ascites or pleural effusions, and fever was absent i...Perinatally infected neonates typically become ill during the first week of life.
May 01, 2020 · Dengue is of particular concern for deploying Service Members, and the development of effective countermeasures to prevent dengue infection is a priority for the Department of Defense.
Infection with any of the 4 dengue virus serotypes results in a diverse range of symptoms, from mild undifferentiated fever to life-threatening hemorrhagic fever and shock. Given that dengue virus infection elicits such a broad range of clinical symptoms, early and accurate laboratory diagnosis is essential for appropriate patient management.
- Global Burden of Dengue
- Prevention and Control
- Who Response
The incidence of dengue has grown dramatically around the world in recent decades. A vast majority of cases are asymptomatic and hence the actual numbers of dengue cases are underreported and many cases are misclassified. One estimate indicates 390 million dengue infections per year (95% credible interval 284–528 million), of which 96 million (67–136 million) manifest clinically (with any severity of disease).1 Another study, of the prevalence of dengue, estimates that 3.9 billion people, in...
The Aedes aegypti mosquito is the primary vector of dengue. The virus is transmitted to humans through the bites of infected female mosquitoes. After virus incubation for 4–10 days, an infected mosquito is capable of transmitting the virus for the rest of its life. Infected symptomatic or asymptomatic humans are the main carriers and multipliers of the virus, serving as a source of the virus for uninfected mosquitoes. Patients who are already infected with the dengue virus can transmit the in...
Dengue fever is a severe, flu-like illness that affects infants, young children and adults, but seldom causes death.Dengue should be suspected when a high fever (40°C/104°F) is accompanied by 2 of the following symptoms: severe headache, pain behind the eyes, muscle and joint pains, nausea, vomiting, swollen glands or rash. Symptoms usually last for 2–7 days, after an incubation period of 4–10 days after the bite from an infected mosquito.Severe dengue is a potentially deadly complication due...
There is no specific treatment for dengue fever.For severe dengue, medical care by physicians and nurses experienced with the effects and progression of the disease can save lives – decreasing mortality rates from more than 20% to less than 1%. Maintenance of the patient's body fluid volume is critical to severe dengue care.
At present, the main method to control or prevent the transmission of dengue virus is to combat vector mosquitoes through: 1. preventing mosquitoes from accessing egg-laying habitats by environmental management and modification; 2. disposing of solid waste properly and removing artificial man-made habitats; 3. covering, emptying and cleaning of domestic water storage containers on a weekly basis; 4. applying appropriate insecticides to water storage outdoor containers; 5. using of personal ho...
WHO responds to dengue in the following ways: 1. supports countries in the confirmation of outbreaks through its collaborating network of laboratories; 2. provides technical support and guidance to countries for the effective management of dengue outbreaks; 3. supports countries to improve their reporting systems and capture the true burden of the disease; 4. provides training on clinical management, diagnosis and vector control at the regional level with some of its collaborating centres; 5....