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Feb 16, 2024 · Common side effects of streptomycin may include: nausea, vomiting, and dizziness; diarrhea; numbness, tingling, or swelling in your face; fever; rash; or. vaginal itching or discharge. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Streptomycin is an aminoglycoside. [3] It works by blocking the ability of 30S ribosomal subunits to make proteins, which results in bacterial death. [3] Albert Schatz first isolated streptomycin in 1943 from Streptomyces griseus. [5] [6] It is on the World Health Organization's List of Essential Medicines. [7]
- 84% to 88% IM (est.) 0% by mouth
- Kidney
- C₂₁H₃₉N₇O₁₂
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Streptomycin injection is used to treat moderate to severe bacterial infections in many different parts of the body. Streptomycin belongs to the class of medicines known as aminoglycoside antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.
May 16, 2023 · Streptomycin passes through the placenta with serum levels in the cord blood similar to maternal levels. Small amounts are excreted in milk, saliva, and sweat. Streptomycin is excreted by glomerular filtration. In patients with normal kidney function, between 29% and 89% of a single 600 mg dose is excreted in the urine within 24 hours.
May 16, 2023 · Streptomycin is a prescription medication used to treat Moderate-Severe Infections, Tuberculosis, Tularemia, Plague, Streptococcal Endocarditis, Enterococcal Endocarditis, and Brucellosis. Streptomycin is available under the following different brand names: N/A
Streptomycin is available as an intramuscular injection, and in some cases may be administered intravenously. 2, 3 A peak serum concentration of 25-50 mcg/mL is achieved within 1 hour after intramuscular administration of 1 gram of streptomycin. 20. Volume of distribution. Not Available. Protein binding.
Pregnancy. Streptomycin can cause fetal harm when administered to a pregnant woman; because streptomycin readily crosses the placental barrier, caution in use of the drug is important to prevent ototoxicity in the fetus; if this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be apprised of the potential hazard to the fetus
