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Streptomycin is an antibiotic medication used to treat a number of bacterial infections, including tuberculosis, Mycobacterium avium complex, endocarditis, brucellosis, Burkholderia infection, plague, tularemia, and rat bite fever.
Jul 4, 2023 · Streptomycin is an aminoglycoside antibiotic originally isolated from the bacteria Streptomyces griseus. It is the first discovered aminoglycoside antibiotic. Its use is primarily treating aerobic gram-negative bacterial infections, such as brucellosis, tularemia, plague ( Y. pestis ), tuberculosis (in combination with isoniazid, pyrazinamide ...
- Mitchell Waters, Prasanna Tadi
- 2023/07/04
The use of streptomycin involves the disruption of protein synthesis within the ribosome, preventing replication of bacteria. It arises from the bacteria Streptomyces griseus and is majorly used in the treatment of infections from aerobic gram-negative bacteria.
General. Type: Aminoglycosides Dosage Forms: IM; Adult Dosing Infections, Bacterial. 1-2 g/day IM divided q6-12h Max: 2 g/day; Info: adjust dose based on serum levels
streptomycin, antibiotic synthesized by the soil organism Streptomyces griseus. Streptomycin was discovered by American biochemists Selman Waksman, Albert Schatz, and Elizabeth Bugie in 1943. The drug acts by interfering with the ability of a microorganism to synthesize certain vital proteins.
- The Editors of Encyclopaedia Britannica
Streptomycin is an aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections. Generic Name. Streptomycin. DrugBank Accession Number. DB01082. Background.
Streptomycin, the first clinically useful drug discovered in the fight against tuberculosis, is an aminoglycoside that has to be given intramuscularly. Streptomycin penetrates cerebrospinal fluid and other remote tissues (e.g. prostate and eye) poorly. There is an immediate and a delayed pathway of excretion via the renal tract.
