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Streptomycin is an aminoglycoside. [3] It works by blocking the ability of 30S ribosomal subunits to make proteins, which results in bacterial death. [3] Albert Schatz first isolated streptomycin in 1943 from Streptomyces griseus. [5] [6] It is on the World Health Organization's List of Essential Medicines. [7]
Jul 4, 2023 · Streptomycin is the first discovered aminoglycoside antibiotic, originally isolated from the bacteria Streptomyces griseus. It is now primarily used as part of the multi-drug treatment of pulmonary tuberculosis. It has additional activity against several aerobic gram-negative bacteria. This activity will discuss the indications, mechanism of action, and contraindications of using streptomycin ...
- Mitchell Waters, Prasanna Tadi
- 2023/07/04
Feb 19, 2019 · Slide culture of a Streptomyces sp. bacteria, which produces the antibiotic streptomycin. Note the branching filamentous hyphae, abundant aerial mycelia, and long chains of small spores. Image: CDC/Dr. David... Top. Cite This Article. DOI: 10.3201/eid2503.et2503. Original Publication Date: February 06, 2019
Jul 21, 2020 · The antibiotic streptomycin was discovered in 1943 by Albert Schatz, a PhD student of Selman Waksman, with help from others including Doris Ralston, Elizabeth Bugie and Christine Reilly . During World War II, there was an urgent drive to find antibiotics that could fill the gap left by penicillin, which was ineffective against tuberculosis (TB ...
- Gerry A. Quinn, Aiya M. Banat, Alyaa M. Abdelhameed, Ibrahim M. Banat
- 10.1099/jmm.0.001232
- 2020
- J Med Microbiol. 2020 Aug; 69(8): 1040-1048.
Streptomisin. Streptomisin (Inggris: Streptomycin) adalah antibiotik yang dihasilkan oleh jamur tanah streptomyces griseus. [2] Antibiotik tersebut diperdagangkan sebagai garam trihidroklorida, fosfat atau sekuisulfat, maupun garam rangkap dengan kalsium klorida. [2]
- 84% to 88% (est.)
- D(US)
Streptomyces merupakan genus penghasil antibiotik terbesar, yang dapat memproduksi obat-obatan antibakteri, antijamur, dan antiparasit, dan juga berbagai senyawa bioaktif lainnya, seperti imunosupresan. Kesalahan pengutipan: Tag <ref> tidak sah; nama tidak sah; misalnya, terlalu banyak.
Laurell G: Pharmacological intervention in the field of ototoxicity. HNO. 2019 Jun;67(6):434-439. doi: 10.1007/s00106-019-0663-1. Serio AW, Keepers T, Andrews L, Krause KM: Aminoglycoside Revival: Review of a Historically Important Class of Antimicrobials Undergoing Rejuvenation.
