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  1. Von Willebrand disease (VWD) is the most common inherited bleeding disorder. VWD is a lifelong disorder but is treatable. In this handout, learn the signs and symptoms of VWD, how it’s diagnosed, and get information on how to best manage VWD. Print Length:

  2. Dec 27, 2023 · Symptoms. The symptoms of von Willebrand disease occur because of excess bleeding. You might experience one or more of the following: Frequent nosebleeds that occur without injury, about five or ...

  3. Specialty. Hematology. Von Willebrand disease ( VWD) is the most common hereditary blood-clotting disorder in humans. An acquired form can sometimes result from other medical conditions. [1] It arises from a deficiency in the quality or quantity of von Willebrand factor (VWF), a multimeric protein that is required for platelet adhesion.

  4. VWD is caused by genetic changes that are almost always inherited (passed down) from a parent to a child. A person’s genes provide instructions on how to make proteins, such as the von Willebrand factor (VWF) protein. Each person has two copies of most genes, one from his or her mother and one from his or her father. Each copy is called an ...

  5. Jan 26, 2024 · Acquired von Willebrand disease (AvWD) is a rare bleeding disorder that prevents the blood from clotting correctly. This can lead to spontaneous and excessive bleeding. The most common causes of ...

  6. Summary. Acquired Von Willebrand syndrome (AVWS) is a bleeding disorder that can occur due to a variety of conditions, but is not caused by a VWF genetic change. This condition may result from lymphoproliferative disorders, autoimmune disorders (including systemic lupus erythrematosus, scleroderma, and antiphospholipid antibody syndrome), heart ...

  7. Named for Dr. Erik von Willebrand, a Finnish doctor who first described the condition in 1926, VWD affects your blood's ability to clot and can lead to heavy, hard-to-stop bleeding after an injury. The bleeding from VWD can lead to damage of your internal organs or even be life threatening, but this is rare.

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