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  2. Intravenous sodium bicarbonate, also known as sodium hydrogen carbonate, is a medication primarily used to treat severe metabolic acidosis. [2] For this purpose it is generally only used when the pH is less than 7.1 and when the underlying cause is either diarrhea, vomiting, or the kidneys. [3]

    • sodium hydrogen carbonate, monosodium carbonate
    • US: ℞-only
  3. Mar 11, 2023 · Sodium bicarbonate administration can be at varying doses for renal tubular acidosis, and to achieve urine alkalization, it can be given IV for some intoxications such as salicylate overdose and as a preventative measure against contrast-induced nephropathy.

  4. Sodium bicarbonate can be administered as a bolus via ampules or through a continuous infusion, depending on the clinical indication and treatment goals. There are several different formulations of IV sodium bicarbonate infusions.

  5. Mar 22, 2019 · Therapy with sodium bicarbonate is indicated for disorders associated with the loss of HCO3- (e.g., diarrhoea, renal tubular acidosis), but the efficacy of sodium bicarbonate therapy to correct metabolic acidosis caused by other reasons has not been established and is the subject of ongoing research [ 4, 7 - 9 ].

    • Sanniya Khan Ghauri, Arslaan Javaeed, Khawaja Junaid Mustafa, Anna Podlasek, Abdus Salam Khan
    • 10.7759/cureus.4297
    • 2019
    • Cureus. 2019 Mar; 11(3): e4297.
  6. Jul 26, 2023 · Used for Metabolic Acidosis. Sodium bicarbonate injection is typically used to lower the amount of acid in the blood when the acid level is too high, which can happen with certain medical conditions such as kidney problems, uncontrolled diabetes, or heart conditions. It can also help restore bicarbonate levels in the body if a person ...

  7. Aug 1, 2023 · Lactic acidosis and cardiac arrest are two common scenarios where there is limited benefit to routine use of sodium bicarbonate, although certain circumstances, such as patients with concomitant acute kidney injury and lactic acidosis may benefit from sodium bicarbonate.

  8. Except in emergencies, Sodium bicarbonate 8.4% should be administered via a central venous catheter as it has an osmolarity of about 2000mOsm/L (ref 2) Hypertonic solution (greater than 1.4%) may cause venous irritation, and extravasation may lead to tissue necrosis

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