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  1. Jun 30, 2011 · Uveal melanoma is the most common primary intraocular malignancy and the leading primary intraocular disease which can be fatal in adults. In this paper epidemiologic, pathogenetic, and clinical aspects of uveal melanoma are discussed. Despite the advance in local ocular treatments, there has been no change in patient survival for three decades.

  2. Uveal melanoma is a malignant tumor arising from melanocytes in the uveal tract (iris, ciliary body, or choroid). It is the most common primary intraocular tumor in adults with an age-adjusted incidence of 5.1 per million. [2] There is a strong tendency for metastasis, particularly to the liver, and prognosis is poor when the tumor has ...

  3. Aug 24, 2021 · Intraocular melanoma is a disease in which malignant (cancer) cells form in the tissues of the eye. Intraocular melanoma begins in the middle of three layers of the wall of the eye. The outer layer includes the white sclera (the "white of the eye") and the clear cornea at the front of the eye. The inner layer has a lining of nerve tissue ...

  4. Mar 13, 2023 · Uveal melanoma is a rare cancer, but it’s the most common primary cancer of the eye in adults. Primary means that the cancer begins in the eye. Sometimes, cancer that starts in the eye can ...

  5. Mar 5, 2014 · Uveal melanoma is the most common primary malignant tumor of the eye in adults, predominantly found in Caucasians. Local tumor control of uveal melanoma is excellent, yet this malignancy is associated with relatively high mortality secondary to metastasis. Various clinical, histopathological, cytogenetic features and gene expression features ...

  6. Jun 6, 2016 · Epidemiologic Characteristics. Melanoma is a malignant tumor arising from melanocytes and may originate from the skin (91%), the eye and tissues surrounding the eye (5%) or the mucosa (1%). 1 In 2% of patients, the source cannot be identified.1 Ophthalmic melanomas can arise in the uvea (85%), eyelid/orbita (10%) and conjunctiva (5%). 1,2 Uveal melanoma is the most common primary intraocular ...

  7. The diagnosis of uveal melanoma is made by recognition of the typical features of this cancer by an experienced eye doctor using indirect ophthalmoscopy. Ophthalmoscopy is a technique whereby the doctor uses a headset with a light and focuses through the pupil into the back of the eye to visualize the tumor.

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