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  1. Oct 14, 2020 · The ventral pallidum (VP) regulates motivation, drug addiction, and several behaviors that rely on heightened arousal. However, the role and underlying neural circuits of the VP in the control...

  2. Feb 2, 2023 · The ventral pallidum (VP) is a central node of the ventral basal ganglia, and recent studies have revealed complex VP cellular heterogeneity and cell- and circuit-specific regulation of reward, aversion, motivation, and drug-seeking behaviors.

  3. Jan 1, 2009 · We review data indicating that 1) an intact ventral pallidum is necessary for normal reward and motivation, 2) stimulated activation of ventral pallidum is sufficient to cause reward and motivation enhancements, and 3) activation patterns in ventral pallidum neurons specifically encode reward and motivation signals via phasic bursts of excitatio...

  4. Jan 8, 2021 · The ventral pallidum (VP) is anatomically poised to contribute to threat behavior. Recent studies report a VP population that scales firing increases to reward but decreases firing to aversive...

  5. Oct 19, 2018 · Nature Communications - In the ventral basal ganglia circuit, the ventral pallidum (VP) receives major inputs from the nucleus accumbens (NAc) and is involved in reward processing. Here,...

  6. Dec 16, 2021 · The ventral pallidum (VP) integrates reward signals to regulate cognitive, emotional, and motor processes associated with motivational salience. Previous studies have revealed that the VP projects axons to many cortical and subcortical structures.

  7. Ventral Pallidum. The VP was originally recognized as a distinct anatomical structure on the basis of its afferent fibers from the two major components of the ventral striatum, the nucleus accumbens and olfactory tubercle, and suggested it served a role similar to the globus pallidus in the striatopallidal circuitry for the dorsal striatum.

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