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1. • • The nucleus accumbens receives afferent projections from the prefrontal cortex, amygdaloid complex (via the ventral amygdalofugal pathway), cells of the bed nucleus of the stria terminalis, amygdalofugal fibers that course through the stria terminalis, the hippocampal formation (via the precommissural fornix), thalamus, and from midbrain (mesencephalon) structures including the ventral tegmental area (VTA) via the medial forebrain bundle and substantia nigra.
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     Nucleus accumbens: anatomy and function | Kenhub

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   What is the nucleus accumbens?

   • This neurotransmitter is then projected to an area called the nucleus accumbens via the mesolimbic pathway. The nucleus accumbens is an area found in the ventral striatum that is strongly associated with motivation and reward and is part of complex circuits involving the amygdala and the hippocampus.

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   Where is the ventral tegmental area located?

   • The ventral tegmental area is in the midbrain between several other major areas, some of which are described here. The mammillary bodies and the posterior hypothalamus, both included in the diencephalon, extend rostrally from the VTA. The red nucleus is situated laterally and oculomotor fibers are situated ventromedially to the VTA.

   Ventral tegmental area - Wikipedia

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   Why is the ventral tegmental area called a 'nucleus'?

   • Originally, the ventral tegmental area was designated as a ‘nucleus’, but over time ‘area’ became the more appropriate term used because of the heterogeneous cytoarchitectonic features of the region and the lack of clear borders that separate it from adjacent regions.

   Ventral tegmental area - Wikipedia

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   Where does the nucleus accumbens receive dopaminergic projections?

   • The nucleus accumbens receives dopaminergic projections from the ventral tegmental area and substantia nigra of the midbrain.

   Nucleus accumbens: anatomy and function | Kenhub

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3. www.kenhub.com › anatomy › nucleus-accumbens-enNucleus accumbens: anatomy and function | Kenhub

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   Oct 30, 2023 · The nucleus accumbens receives dopaminergic projections from the ventral tegmental area and substantia nigra of the midbrain. This connection forms part of a major dopaminergic pathway called the mesolimbic pathway (reward pathway), which connects the VTA with regions of the limbic system including the nucleus accumbens, hypothalamus, amygdala ...

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4. en.wikipedia.org › wiki › Ventral_tegmental_areaVentral tegmental area - Wikipedia

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   The nucleus accumbens and the ventral tegmental area are the primary sites where addictive drugs act. The following are commonly considered to be addictive: cocaine , alcohol , opioids , nicotine , cannabinoids , amphetamine , and their analogs.

   • Acronym(s): VTA
   • MeSH: D017557

   • Latin: Area tegmentalis ventralis
   • Part of: Midbrain

5. www.ncbi.nlm.nih.gov › pmc › articlesThe Ventral Tegmental Area and Nucleus Accumbens as Circadian ...

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   Apr 27, 2022 · In this review, we present the most recent evidence for the ventral tegmental area (VTA) and nucleus accumbens (NAc) to serve as extra-SCN oscillators and highlight studies that illustrate the functional significance of the VTA’s and NAc’s inherent circadian properties as they relate to reward-processing, drug abuse, and vulnerability to ...

   • DOI: 10.3389/fphys.2022.886704
   • Published: 2022

   • Publication: Front Physiol. 2022; 13: 886704.

6. www.simplypsychology.org › brain-reward-systemBrain Reward System - Simply Psychology

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   Sep 14, 2023 · The nucleus accumbens is an area found in the ventral striatum that is strongly associated with motivation and reward and is part of complex circuits involving the amygdala and the hippocampus. The activation of the nucleus accumbens causes dopamine levels in this region to rise.

7. www.nature.com › articles › nrnVentral tegmental area: cellular heterogeneity, connectivity ...

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   Jan 5, 2017 · Nature Reviews Neuroscience - Neurons in the ventral tegmental area (VTA) are highly heterogeneous and project to a range of different brain regions. Morales and Margolis summarize recent...

   • Author: Marisela Morales, Elyssa B. Margolis

   • Publish Year: 2017

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9. en.wikipedia.org › wiki › Nucleus_accumbensNucleus accumbens - Wikipedia

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   The ventral striatum and dorsal striatum collectively form the striatum, which is the main component of the basal ganglia. [2] . The dopaminergic neurons of the mesolimbic pathway project onto the GABAergic medium spiny neurons of the nucleus accumbens and olfactory tubercle.

10. www.ncbi.nlm.nih.gov › pmc › articlesEvidence and explanation for the involvement of the nucleus ...

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    Oct 18, 2019 · ACC: Anterior cingulate cortex; Amy: amygdala; DH: dorsal horn of the spinal cord; Hab: habenula; Hyp: hypothalamus; Ins: insular cortex; LC: locus coeruleus; NAc: nucleus accumbens; NRM: nucleus raphe magnus; PAG: periaqueductal gray; RVM: rostral ventral medulla; S1: primary somatosensory cortex; Thal: thalamus.