Jul 08, 2021 · The ventral tegmental area also plays a major role in controlling and releasing glutamate and GABA neurotransmitters. These neurotransmitters are co-released with dopamine and have their fair amount of share in maintaining the healthy functioning of our brain. GABA is primarily responsible for maintaining the inhibition of an individual.
Long-range projections of ventral tegmental area (VTA) glutamate neurons and their functions. VTA glutamate neurons project to the ventral pallidum, the nucleus accumbens, the prefrontal cortex, the lateral habenula and the dorsal hippocampus. The shapes and locations can only represent the general structure and location.
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The primary role of the ventral tegmental area (VTA) is the assessment of need. The VTA processes information to ensure satisfaction; it then forwards this information to the nucleus accumbens (NA) using the neurotransmitter dopamine. If there is an increase in dopamine in the VTA there is a concurrent increase in the NA.
- Anatomy of The Ventral Tegmental Area
- Functions of This Structure
- The Brain Reward System
- Associated Disorders
The concept "ventral tegmental area" refers to a set of neurons that are located at the base of the midbrain, the intermediate region of the brain stem. In Latin the word "tegmentum" means "covering" or "covering"; therefore, the name highlights the fact that this area constitutes a layer of neurons that covers the midbrain. Four main cell nuclei h...
Dopaminergic neurons of the ventral tegmental area are part of the mesocortical and mesolimbic systems. While the mesocortical system connects this region with the frontal lobes, the mesolimbic system sends projections to the nucleus accumbens, a fundamental structure of the brain's reward system, as does the ventral tegmental area. The mesocortica...
The ventral tegmental area is a key structure of the brain's reward system, the biological basis of pleasure and behavioral motivation, sinceappetitive stimuli activate this region. In this way, the reward circuit is involved in multiple behaviors, such as those related to food, sex or addictions. When the body detects pleasant stimulation, the ven...
Scientific research has identified several disorders that present with alterations in the dopaminergic pathways of which the ventral tegmental area is a part. In general, these types of disorders involve both the mesolimbic and mesocortical pathways, which are closely linked. The neuropsychological disorders most frequently attributed to structural...
The ventral tegmental area (VTA) is a brain region centrally involved in the development and expression of a variety of behaviors associated with drug use. Hypocretin (hcrt), also known as orexin, is a lateral hypothalamic neuropeptide that can be released into the VTA.