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What is the structure and role of the ventral tegmental area?
What is the clinical significance of the ventral tegmental area (VTA)?
How many types of neurons are in the ventral tegmental area?
1 day ago · The dorsal raphe nucleus (DRN) is a major source of serotonergic projections to brain-wide targets, including the frontal cortex, the basal ganglia, the ventral tegmental area (VTA), and other mid ...
2 days ago · Decades of investigations have revealed that midbrain dopamine neurons in the ventral tegmental area (VTA) generally encode reward prediction errors (Schultz et al., 1997): the neurons increase their firing to unexpected reward delivery and shift their response to cues that precede reward delivery after instrumental learning or classical ...
4 days ago · From the standpoint of future treatments in patients with severe brain injuries, the researchers showed that a dopamine-producing region in the brainstem, the ventral tegmental area, is a connectivity hub that links the subcortical default ascending arousal network to the cortical default mode network.
3 days ago · Primed by OXT, the medial preoptic area of the hypothalamus projects to the amygdala to increase vigilance to infant signals, and to mesolimbic dopaminergic reward circuits [including ventral striatum and ventral tegmental area (VTA)] to increase reward from infant interactions.
2 days ago · This finding has shed new light on the pathophysiological mechanisms of alcohol dependence and depressive disorders. The reward network, also known as the mesolimbic dopamine system, originates in the ventral tegmental area of the midbrain and projects to the striatum, nucleus accumbens, cingulate gyrus, amygdala, and prefrontal cortex
5 days ago · Together, this work provides a detailed look into the transcriptional landscape of the fentanyl experienced ventral tegmental area and will serve as a launching point for many future mechanistic investigations. Our primary goal in this work was to uncover cell type-specific changes in gene expression in the VTA as a function of fentanyl experience.
3 days ago · The brain stem includes the medulla and pons, located ventral to the cerebellum. In addition to housing essential ascending and descending tracts, the brain stem contains nuclei that are essential for maintenance of life. As a result of the relatively tight packaging of numerous ascending and descending tracts, as well as nuclei, within the ...
