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May 27, 2019 · The CoV envelope (E) protein is a small, integral membrane protein involved in several aspects of the virus’ life cycle, such as assembly, budding, envelope formation, and pathogenesis. Recent studies have expanded on its structural motifs and topology, its functions as an ion-channelling viroporin, and its interactions with both other CoV ...
- Dewald Schoeman, Burtram C. Fielding
- 2019
May 27, 2019 · The CoV envelope (E) protein is a small, integral membrane protein involved in several aspects of the virus’ life cycle, such as assembly, budding, envelope formation, and pathogenesis. Recent studies have expanded on its structural motifs and topology, its functions as an ion-channelling viroporin, and its interactions with both other CoV ...
- Dewald Schoeman, Burtram C. Fielding
- 10.1186/s12985-019-1182-0
- 2019
- Virol J. 2019; 16: 69.
The envelope (E) protein is the smallest and least well-characterized of the four major structural proteins found in coronavirus virions. [2] [3] [4] It is an integral membrane protein less than 110 amino acid residues long; [2] in SARS-CoV-2 , the causative agent of Covid-19 , the E protein is 75 residues long. [5]
May 27, 2019 · The CoV envelope (E) protein is a small, integral membrane protein involved in several aspects of the virus' life cycle, such as assembly, budding, envelope formation, and pathogenesis. Recent studies have expanded on its structural motifs and topology, its functions as an ion-channelling viroporin, and its interactions with both other CoV ...
- Dewald Schoeman, Burtram C. Fielding
- 2019
Sep 17, 2021 · Four ORFs at the 3′ terminus of the viral genome encode a canonical set of structural proteins that include the nucleocapsid (N), spike (S) protein, membrane (M) protein and envelope (E) protein ...
- Haitao Yang, Zihe Rao
- 2021
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Nov 11, 2020 · An essential protein of the SARS-CoV-2 virus, the envelope protein E, forms a homopentameric cation channel that is important for virus pathogenicity. Here we report a 2.1-Å structure and the ...
Apr 1, 2020 · Coronavirus proteins. SARS-CoV-2 has four structural proteins (top): the E and M proteins, which form the viral envelope; the N protein (detail not shown), which binds to the virus’s RNA genome ...
