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Jul 8, 2019 · Vitamin D supplementation in low/moderate doses is not thought to be harmful to patients, has wider health benefits, is relatively inexpensive and has fewer side effects/interactions compared with many other commonly used treatments for RA, such as non-steroidal anti-inflammatory drugs (NSAIDs), or conventional synthetic or biological disease ...
- Fig. 1
Role of vitamin D in the immune system. Schematic...
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Normal vit D assoc. with ↓recurrence. No difference was...
- Fig. 1
Oct 30, 2020 · There are also studies based on rheumatoid arthritis that suggest that active vitamin D can be used as a parameter for regulating inflammation and that vitamin D has the potential to be a therapeutic biomarker and can even be used to track the disease progression and treatment effect of rheumatoid arthritis patients . In previous systematic ...
- Yuanyuan Guan, Yang Hao, Yun Guan, Huaien Bu, Hongwu Wang
- 10.3389/fmed.2020.596007
- 2020
- Front Med (Lausanne). 2020; 7: 596007.
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1) Folic acid
Not everyone with rheumatoid arthritis needs to take folic acid, which is the synthetic form of folate, a type of B vitamin that is involved in such critical functions as cell division and the production of new red blood cells. But if your rheumatologist prescribes the disease-modifying drug methotrexate to treat your arthritis, they’ll most likely recommend you take folic acid supplements to prevent a folate deficiency. “One of methotrexate’s most important mechanisms of action also inhibits...
2) Calcium
Doctors and nutritionists generally prefer that people get their calcium from food rather than supplements, but there are exceptions. “If you have RA and you’re diagnosed with osteopenia or osteoporosis — or you’re already being treated for osteoporosis — your doctor may recommend you take calcium supplements,” says Dr. Davis. People with inflammatory arthritis who are treated with glucocorticoids — steroids that are often used to stop arthritis flares — may also need to take a calcium supple...
3) Vitamin D
While studies suggest that many Americans may be deficient in D, the problem appears to be even more prevalent among people with rheumatoid arthritis, according to a study published in the journal Therapeutic Advances in Endocrinology and Metabolism. Dr. Davis says it’s not understood why this association exists (one theory is that the inflammation of RA may decrease levels of vitamin D), but it is worrisome. “It’s an area of ongoing research,” he says. “We are concerned that people with RA t...
5) Turmeric
This trendy spice has been touted for its antioxidant compounds and anti-inflammatory properties. And there’s a chance it may just live up to the hype when it comes to easing pain from RA. “It’s quite possible that there is some chemical component in turmeric that works like ibuprofen or an even stronger drug we have yet to identify,” Dr. Davis says. Studies that demonstrate turmeric’s effectiveness in people with inflammatory arthritis are very small. However, a review of existing studiessho...
6) CBD (cannabidiol) oil
CBD oil has been a hot topic lately; many proponents claim that this component of the cannabis plant can treat everything from anxiety to inflammation. However, Dr. Davis says there’s not much data supporting its use in people with RA yet; the studies that do exist are small. But CBD oil does have some potential: A 2016 research review in the journal Arthritis Care & Researchsuggested that cannabinoid treatments could provide some pain relief and improve sleep in those with RA. The concern is...
Sep 13, 2016 · Background Osteoarthritis (OA) of the knee joint is a degenerative process resulting in cartilage loss. Recent evidence suggests that OA is not merely a disease of cartilage but a disease of the entire knee joint and that inflammation may play an important role. OA has been associated with vitamin D deficiency. Vitamin D as an immunomodulator and anti-inflammatory agent may attenuate ...
- Vikrant Rai, Nicholas E. Dietz, Matthew F. Dilisio, Matthew F. Dilisio, Mohamed M. Radwan, Devendra ...
- 2016
Jul 2, 2015 · Here, we look specifically at the changes in cellular behaviour in osteoarthritis ( ). Figure 2. The effects of vitamin D on several different cell types in osteoarthritis including chondrocytes, osteoclasts, and osteoblasts. Vitamin D has a range of effects on cell types within osteoarthritis affected joints. Vitamin D acts through the vitamin ...
- Thomas Mabey, Sittisak Honsawek
- 10.1155/2015/383918
- 2015
- Int J Endocrinol. 2015; 2015: 383918.
Jun 8, 2022 · That’s when acute inflammation becomes long-term, or chronic. Inflammation-Related Diseases . Chronic inflammation may be responsible for around 80% or more of noncommunicable diseases, including: Inflammatory forms of arthritis, such as rheumatoid arthritis, psoriatic arthritis and gout; Obesity; Heart disease; Type 1 and type 2 diabetes
Jul 8, 2019 · Vitamin D has been reported to influence physiological systems that extend far beyond its established functions in calcium and bone homeostasis. Prominent amongst these are the potent immunomodulatory effects of the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3). The nuclear vitamin D receptor (VDR) for 1,25-(OH)2D3 is expressed by many cells within the immune system and ...
