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   Can von Willebrand disease be cured?

   • Even though von Willebrand disease has no cure, treatment can help prevent or stop bleeding episodes. Your treatment depends on: Your doctor might suggest one or more of the following treatments to increase your von Willebrand factor, strengthen blood clots or control heavy menstrual bleeding: Desmopressin.

   Von Willebrand disease - Diagnosis & treatment - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/von-willebrand-disease/diagnosis-treatment/drc-20354984

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   What is a therapeutic adjuvant for von Willebrand disease?

   • Therapeutic adjuvants are platelet concentrates, combined estrogen–progestogen drugs, and antifibrinolytic agents such as tranexamic acid and epsilon aminocaproic acid. Table 1. Mean characteristic of concentrates of von Willebrand factor/factor VIII and von Willebrand factor alone approved for the treatment of von Willebrand disease.

   Prophylactic management of patients with von Willebrand disease

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8721401/

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   Does von Willebrand disease cause bleeding-related hospitalization?

   • Holm E, Carlsson KS, Lövdahl S, et al. Bleeding-related hospitalization in patients with von Willebrand disease and the impact of prophylaxis: results from national registers in Sweden compared with normal controls and participants in the von Willebrand Disease Prophylaxis Network. Haemophilia 2018; 24: 628–633. [ PubMed] [ Google Scholar] 62.

   Prophylactic management of patients with von Willebrand disease

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8721401/

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2. ashpublications.org › hematology › articlePerioperative management of patients with von Willebrand disease

   ashpublications.org › hematology › article

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   Dec 6, 2019 · Review preoperative risk assessment strategies to guide hemostatic cover at the time of surgery for people with von Willebrand disease. Understand the distinctions between differing von Willebrand factor replacement therapies and the timing of administration preoperatively

   • Author: James S. O’Donnell, Michelle Lavin

   • Publish Year: 2019

3. www.ncbi.nlm.nih.gov › pmc › articlesSurgical management of patients with von Willebrand disease ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jan 1, 2022 · The management of patients with VWD who are undergoing surgeries is crucial to prevent bleeding complications. We systematically summarized the evidence on the management of patients with VWD who are undergoing major and minor surgeries to support the development of practice guidelines.

   • DOI: 10.1182/bloodadvances.2021005666
   • Published: 2022/01/01

   • Publication: Blood Adv. 2022 Jan 11; 6(1): 121-128.

4. onlinelibrary.wiley.com › doi › fullPerioperative management for patients with von Willebrand ...

   onlinelibrary.wiley.com › doi › full

   Jun 4, 2020 · This review provides an overview of the current evidence for the surgical management of patients with VWD and, summarises the optimal treatment approach during the perioperative period, and highlights key unanswered questions and the research needed to address the evidence gaps.

   • Author: Wolfgang Miesbach

   • Publish Year: 2020

5. www.uptodate.com › contents › von-willebrand-diseasePatient education: von Willebrand disease (Beyond the Basics)

   www.uptodate.com › contents › von-willebrand-disease

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   Apr 16, 2024 · Approach to the adult with a suspected bleeding disorder. Pathophysiology of von Willebrand disease. Clinical presentation and diagnosis of von Willebrand disease. von Willebrand disease (VWD): Treatment of major bleeding and major surgery.

6. www.mayoclinic.org › diseases-conditions › vonVon Willebrand disease - Diagnosis & treatment - Mayo Clinic

   www.mayoclinic.org › diseases-conditions › von

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   Oct 26, 2021 · Let your doctors or dentist know that you have von Willebrand disease before you have surgery, start a new medication or give birth. Also mention whether anyone in your family has a history of excessive bleeding.

7. www.ncbi.nlm.nih.gov › pmc › articlesProphylactic management of patients with von Willebrand disease

   www.ncbi.nlm.nih.gov › pmc › articles

   Dec 22, 2021 · Unlike patients with severe hemophilia, most patients with VWD generally have less frequent and clinically severe bleeding, so that they usually receive treatment episodically at the time of bleeding, in anticipation of invasive procedures, at menstruation, during and after labor, or after trauma.

8. www.hematology.org › - › mediaASH ISTH NHF WFH 2021 guidelines on the management of von ...

   www.hematology.org › - › media

   Major therapies include use of desmopressin to induce endothelial release of stored von Willebrand factor (VWF) and factor VIII (FVIII) and use of VWF concentrates, including both plasma-derived and recombinant products, as well as adjuvant therapies, such as antifibrinolytic tranexamic acid.