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  1. While there is no cure for vWD, dogs can have a normal lifespan with proper care. Causes A protein called the von Willebrand Factor (vWF) plays an important role in clot formation. For dogs with vWD, this protein can be reduced, dysfunctional or absent all together.

  2. Background. von Willebrand Disease (abbreviated vWD) is an inherited bleeding disorder caused by lack of von Willebrand factor protein (vWF). This protein circulates in the blood stream and must be present at the site of blood vessel injury in order to control bleeding from that vessel.

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  4. Nov 11, 2017 · Summary. VWD is a common and challenging bleeding disorder, given the difficulties in diagnosis and treatment. New options for diagnosis, including use of bleeding assessment tools and new assays for VWF activity, may help alleviate some of these challenges.

    • Ruchika Sharma, Ruchika Sharma, Veronica H. Flood, Veronica H. Flood, Veronica H. Flood
    • 10.1182/blood-2017-05-782029
    • 2017
    • Blood. 2017 Nov 30; 130(22): 2386-2391.
  5. Synopsis. Von Willebrand disease (VWD) is a common bleeding disorder, affecting males and females equally, that often manifests in mucosal bleeding. VWD can be secondary to a quantitative (Type 1 and Type 3) or qualitative (Type 2) defects in Von Willebrand factor.

    • Angela C. Weyand, Veronica H. Flood
    • 2021/12
    • 10.1016/j.hoc.2021.07.004
  6. Von Willebrand Disease is an inherited bleeding disorder that makes it difficult for blood to clot. It is the most common inherited bleeding disorder in dogs, and affected dogs may show signs of bleeding — such as skin bruising, bleeding from the gums or nose, and excessive bleeding during surgery.

  7. von Willebrand disease (VWD) represents the most common inherited bleeding disorder ( Lillicrap 2013 ). It is caused by quantitative or qualitative reductions in plasma von Willebrand factor (VWF) ( Leebeek and Eikenboom 2016 ). Studies suggest that reduced plasma VWF levels have a population prevalence of 1% ( Bowman, et al 2010, Rodeghiero ...

  8. Von Willebrand's disease (vWD) is the most common inherited bleeding disorder of both humans and dogs. It is caused by a deficiency in the amount of a specific protein needed to help platelets (the blood cells used in clotting) stick together and form clots to seal broken blood vessels.

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