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      • Laboratory diagnosis of vWD is most often based on results of von Willebrand factor antigen assay (abbreviated vWF:Ag). This test measures the amount or concentration of vWF in a blood sample. The Comparative Coagulation Section reports each dog's result as %vWF:Ag compared to a 100% standard.
      ahdc.vet.cornell.edu/sects/coag/clinical/vonwill/labdiag.cfm
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  2. Laboratory Diagnosis. Laboratory diagnosis of vWD is most often based on results of von Willebrand factor antigen assay (abbreviated vWF:Ag). This test measures the amount or concentration of vWF in a blood sample. The Comparative Coagulation Section reports each dog's result as %vWF:Ag compared to a 100% standard.

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    • 70 to 180
    • 50 to 69
  3. Von Willebrand's disease causes an inability for blood to clot resulting in inappropriate bleeding. It is most commonly seen in Dobermans. If this disease is suspected, initial screening tests include complete blood count (CBC), buccal mucosal bleeding time, and a coagulation profile.

  4. Dogs with vWF/vWF genotype may be affected and develop Von Willebrand disease Type I, a blood clotting disorder, and will transmit this variant to all of their offspring. Results of this test can be submitted to the OFA (Orthopedic Foundation for Animals) Price. $50 one test per animal.

  5. Von Willebrand's disease (vWD) is the most common inherited bleeding disorder of both humans and dogs. It is caused by a deficiency in the amount of a specific protein needed to help platelets (the blood cells used in clotting) stick together and form clots to seal broken blood vessels. The deficient protein is called von Willebrand factor (vWF).

  6. Dogs with N/N genotype will not have Von Willebrand disease Type 2 and cannot transmit this variant to their offspring. Dogs with N/vWF genotype are unlikely to develop Von Willebrand disease Type 2, but are carriers.

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