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Does von Willebrand disease affect pregnancy and childbirth?
Can a woman with von Willebrand disease have a vaginal delivery?
Does von Willebrand disease cause abnormal uterine bleeding?
Does von Willebrand disease cause postpartum hemorrhage?
The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.
- Table 1
Given the wide heterogeneity of phenotypes and of the...
- Mcmdm-1Vwd
Introduction. von Willebrand factor (VWF) is a multimeric...
- Table 1
Many experts advocate that women with von Willebrand disease may have a vaginal delivery safely, with cesarean delivery reserved for standard indications 7 10. Because von Willebrand disease can be transmitted as an autosomal dominant or recessive trait, the fetus can have up to a 50% risk of being affected.
- Pregnancy and Childbirth
- After Delivery
- Tips
With proper care, women with von Willebrand disease (VWD) can have a successful pregnancy and deliver a healthy child. A woman who has VWD should be monitored closely throughout her pregnancy by her doctors. It is important for a woman’s health care providers to be aware that she has VWD so that plans can be made for a safe delivery. If a woman is ...
Women with VWD are at risk for serious bleeding after delivery. During any pregnancy, the body makes higher amounts of clotting factors to prevent bleeding. However, the high levels of clotting factors during pregnancy drop back to lower levels after delivery. If the woman has low levels of clotting factor, then she can bleed after delivery or surg...
To reduce the chances of having problems during pregnancy and after delivery, a woman with VWD should: 1. Talk to her doctor about her bleeding disorder before becoming pregnant. 2. Think about seeing a doctor who specializes in high-risk pregnancies and a hospital that has a hematologist (a doctor who specializes in bleeding disorders) on staff fo...
Nov 5, 2020 · Women with inherited bleeding disorders, including carriers of hemophilia A and B, or with von Willebrand disease, have an increased risk of bleeding during pregnancy and delivery. The unborn child may also be affected by the bleeding disorder for which specific measures have to be considered.
- Frank W G Leebeek, Johannes Duvekot, Marieke J H A Kruip
- 2020
May 1, 2017 · A 37-year-old woman 28 weeks into her first pregnancy is referred to hematology clinic given a history of von Willebrand disease (vWD) diagnosed during her teenage years, after presenting with excessive menstrual bleeding requiring oral iron supplementation.
- Caroline Berube, Brian Dietrich
- 2017
May 25, 2022 · von Willebrand disease (VWD) is a bleeding disorder. It can be inherited or, less commonly, develop later in life (this type of VWD is not heritable and is referred to as acquired von Willebrand syndrome [AVWS]).
Jun 7, 2022 · Background and Objectives Several reports indicate that women with von Willebrand disease (VWD) are at an increased risk of bleeding and other complications during pregnancy and childbirth. The aim of this study was to investigate the effect of VWD on the course of pregnancy, childbirth, and the postpartum period.
