Ads
related to: von willebrand in pregnancy causes and curesVisit the VONVENDI® [von Willebrand factor (Recombinant)] website for patient resources.
Treatment may prevent and treat thromboembolism in patients with hereditary antithrombin. deficiency (HATD) during pregnancy, childbirth, and after delivery. Learn more
Search results
General guidelines for the treatment of women with von Willebrand disease at delivery. Since pregnant women with VWD are at increased risk of postpartum hemorrhage if untreated 9, 17, 27, 31, treatment options should be planned at the beginning of pregnancy.
- Table 1
Given the wide heterogeneity of phenotypes and of the...
- Mcmdm-1Vwd
Introduction. von Willebrand factor (VWF) is a multimeric...
- Table 1
May 20, 2019 · The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.
- Giancarlo Castaman, Paula D. James
- 2019
Von Willebrand disease is a prevalent condition in females of childbearing age, and during pregnancy, it is associated with a higher risk of postpartum bleeding, exposure to massive transfusion protocols, pulmonary edema, acute renal injury, postpartum bleeding-related maternal mortality, and transfusion-related complications .
Jun 7, 2022 · Although VWD occurs equally in males and females, women are at a higher risk of being affected, mostly because of bleeding challenges associated with menstruation, pregnancy, and childbirth [ 1, 7, 8 ]. During pregnancy, many changes in hemostasis occur that result in a hypercoagulable state.
Nov 5, 2020 · Carriers of hemophilia A (HA) or hemophilia B (HB) and women suffering from von Willebrand disease (VWD) have an increased risk for bleeding during pregnancy and delivery. Management of these women concerns not only managing the bleeding tendency of the mother, but also that of the child with a potential bleeding disorder.
- Frank W G Leebeek, Johannes Duvekot, Marieke J H A Kruip
- 2020
Oct 26, 2021 · The usual cause of von Willebrand disease is an inherited abnormal gene that controls von Willebrand factor — a protein that plays a key role in blood clotting. When you have low levels of this protein or it doesn't work as it should, small blood cells called platelets cannot stick together properly nor attach themselves normally to the blood ...
Reynen E, James P. Von Willebrand disease and pregnancy: a review of evidence and expert opinion. Semin Thromb Hemost . 2016;42(7):717-723. Stoof SC, van Steenbergen HW, Zwagemaker A, et al. Primary postpartum haemorrhage in women with von Willebrand disease or carriership of haemophilia despite specialised care: a retrospective survey.
