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General guidelines for the treatment of women with von Willebrand disease at delivery. Since pregnant women with VWD are at increased risk of postpartum hemorrhage if untreated 9, 17, 27, 31, treatment options should be planned at the beginning of pregnancy.
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Given the wide heterogeneity of phenotypes and of the...
- Mcmdm-1Vwd
Introduction. von Willebrand factor (VWF) is a multimeric...
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Reynen E, James P. Von Willebrand disease and pregnancy: a review of evidence and expert opinion. Semin Thromb Hemost . 2016;42(7):717-723. Stoof SC, van Steenbergen HW, Zwagemaker A, et al. Primary postpartum haemorrhage in women with von Willebrand disease or carriership of haemophilia despite specialised care: a retrospective survey.
Oct 26, 2021 · Your treatment depends on: The type and severity of your condition. How you've responded to previous therapy. Your other medications and conditions. Your doctor might suggest one or more of the following treatments to increase your von Willebrand factor, strengthen blood clots or control heavy menstrual bleeding: Desmopressin.
May 1, 2017 · A 37-year-old woman 28 weeks into her first pregnancy is referred to hematology clinic given a history of von Willebrand disease (vWD) diagnosed during her teenage years, after presenting with excessive menstrual bleeding requiring oral iron supplementation.
- Caroline Berube, Brian Dietrich
- 2017
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Jun 16, 2023 · This topic reviews the clinical presentation, diagnosis, and differential diagnosis of VWD. Separate topic reviews discuss the treatment and pathophysiology of VWD, the diagnosis and treatment of acquired von Willebrand syndrome (AVWS), and a general approach to bleeding disorders. Treatment of VWD – (See "von Willebrand disease (VWD ...
May 20, 2019 · The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.
Oct 26, 2021 · Causes. The usual cause of von Willebrand disease is an inherited abnormal gene that controls von Willebrand factor — a protein that plays a key role in blood clotting.
