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The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.
- Table - PMC - National Center for Biotechnology Information
Given the wide heterogeneity of phenotypes and of the...
- Identification of type 1 von Willebrand disease patients with reduced ...
Introduction. von Willebrand factor (VWF) is a multimeric...
- The Effect of Von Willebrand Disease on Pregnancy, Delivery ...
Although VWD occurs equally in males and females, women are...
- Gynecologic and obstetric management of women with von ...
von Willebrand disease (VWD) disproportionately affects...
- Table - PMC - National Center for Biotechnology Information
Apr 26, 2010 · hemorrhage. pregnancy. von Willebrand disease. A 26-year-old patient was seen for routine prenatal care. She had a history of delayed postpartum hemorrhage 4 years earlier after an uncomplicated vaginal delivery. During a recent visit to the dentist, she experienced increased bleeding after a tooth extraction.
May 1, 2017 · During pregnancy, hormonal influences lead to an increase in vWF and clotting factors VII, VIII, and X while anticoagulant factors (such as protein S) decrease, shifting hemostasis to a procoagulant state to compensate for anticipated hemorrhage during parturition. 3 Although vWF and FVIII levels rise and peak during the third trimester, women w...
- Caroline Berube, Brian Dietrich
- 2017
April 2018 - Volume 16, Issue 4. Current Approaches to Pregnancy and Childbirth in Women With von Willebrand Disease. Jill M. Johnsen, MD. Associate Member. Bloodworks Northwest. Associate Professor of Medicine. Division of Hematology. University of Washington School of Medicine. Seattle, Washington. Download PDF.
May 20, 2019 · The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.
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Visit our website to view safety information for a treatment for adults with VWD.