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  2. View administration and reconstitution information for a treatment for VWD in adults.

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  2. Oct 26, 2021 · The usual cause of von Willebrand disease is an inherited abnormal gene that controls von Willebrand factor — a protein that plays a key role in blood clotting. When you have low levels of this protein or it doesn't work as it should, small blood cells called platelets cannot stick together properly nor attach themselves normally to the blood ...

  3. Von Willebrand disease (VWD), the most frequent autosomal inherited bleeding disorder, is caused by quantitative or qualitative defects of von Willebrand factor (VWF), an adhesive protein that binds platelets to exposed sub-endothelium and carries factor VIII (FVIII) in circulation 1, 2.

    • Giancarlo Castaman, Paula D. James
    • 10.1111/ejh.13250
    • 2019
    • 2019/08
  4. Jun 22, 2022 · What are the symptoms of von Willebrand disease? Many people with von Willebrand disease have the condition, but don’t have symptoms or have mild symptoms. People who have a more severe form of the condition may have the following symptoms: Nosebleeds: These are nosebleeds that last longer than 10 minutes and happen five or more times a year.

  5. May 20, 2019 · Given the wide heterogeneity of phenotypes and of the underlying pathophysiological mechanisms associated with the disorder, pregnancy and delivery in von Willebrand disease (VWD) represent a significant clinical challenge.

    • Giancarlo Castaman, Paula D. James
    • 2019
  6. Mar 31, 2017 · Types. Symptoms. Causes. Diagnosis. Treatments. Outlook. What is von Willebrand disease? Von Willebrand disease is a bleeding disorder. It’s caused by a deficiency of von Willebrand...

  7. Jul 23, 2023 · The most common symptoms of von Willebrand disease in decreasing frequency include: Heavy or prolonged menstrual bleeding (previously called menorrhagia ) Frequent and easy bruising (from minimal trauma)

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  2. View administration and reconstitution information for a treatment for VWD in adults.

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