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There are three main types of von Willebrand disease. Type 1 (deficiency of vWF), the most common, is usually mild; type 2 (abnormal vWF) has several subtypes and is less common; and type 3 (absence of vWF), which is rare, is the most severe form 1. Presenting Symptoms and Signs.
General guidelines for the treatment of women with von Willebrand disease at delivery. Since pregnant women with VWD are at increased risk of postpartum hemorrhage if untreated 9, 17, 27, 31, treatment options should be planned at the beginning of pregnancy.
- Giancarlo Castaman, Paula D. James
- 10.1111/ejh.13250
- 2019
- 2019/08
Jun 16, 2023 · Patient education: von Willebrand disease (Beyond the Basics) Abnormal uterine bleeding in nonpregnant reproductive-age patients: Terminology, evaluation, and approach to diagnosis; Acquired von Willebrand syndrome; Acute phase reactants; Approach to the adult with a suspected bleeding disorder; Approach to the child with bleeding symptoms
Jan 12, 2021 · von Willebrand disease (VWD) is the most common inherited bleeding disorder known in humans. Accurate and timely diagnosis presents numerous challenges. Objective:
- Paula D James, Nathan T Connell, Barbara Ameer, Barbara Ameer, Jorge Di Paola, Jeroen Eikenboom, Nic...
- 2021
Oct 26, 2021 · To evaluate you for von Willebrand disease, your doctor will likely ask you detailed questions about your medical history and check for bruises or other signs of recent bleeding. Your doctor will also likely recommend the following blood tests: Von Willebrand factor antigen.
In type 1—which is the most common by far, accounting for approximately 75% of cases—the level of von Willebrand factor (VWF) is low, but the protein functions normally. In type 2, which accounts for approximately 20% of cases, the VWF level may be normal, but the protein functions abnormally.
With proper care, women with von Willebrand disease (VWD) can have a successful pregnancy and deliver a healthy child. A woman who has VWD should be monitored closely throughout her pregnancy by her doctors. It is important for a woman’s health care providers to be aware that she has VWD so that plans can be made for a safe delivery.
