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  1. General guidelines for the treatment of women with von Willebrand disease at delivery. Since pregnant women with VWD are at increased risk of postpartum hemorrhage if untreated 9, 17, 27, 31, treatment options should be planned at the beginning of pregnancy.

    • Table 1

      Given the wide heterogeneity of phenotypes and of the...

    • Mcmdm-1Vwd

      Introduction. von Willebrand factor (VWF) is a multimeric...

  2. Nov 5, 2020 · Carriers of hemophilia A (HA) or hemophilia B (HB) and women suffering from von Willebrand disease (VWD) have an increased risk for bleeding during pregnancy and delivery. Management of these women concerns not only managing the bleeding tendency of the mother, but also that of the child with a potential bleeding disorder.

    • Frank W G Leebeek, Johannes Duvekot, Marieke J H A Kruip
    • 2020
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  4. May 20, 2019 · In a retrospective study of 27 women with VWD, higher rates of miscarriage and bleeding throughout pregnancy were reported 9; however, caution should be exercised when interpreting these results as women with VWD may bleed more after a pregnancy complication and come to medical attention more readily.

    • Giancarlo Castaman, Paula D. James
    • 2019
  5. Jun 7, 2022 · Women with VWD have levels of blood clotting factor VIII (FVIII), von Willebrand factor (VWF:Ag), and von Willebrand factor ristocetin cofactor activity (VWF:RCo) measured at the time of delivery or at least two weeks before expected delivery, and more frequently if complications occur.

    • Pregnancy and Childbirth
    • After Delivery
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    With proper care, women with von Willebrand disease (VWD) can have a successful pregnancy and deliver a healthy child. A woman who has VWD should be monitored closely throughout her pregnancy by her doctors. It is important for a woman’s health care providers to be aware that she has VWD so that plans can be made for a safe delivery. If a woman is ...

    Women with VWD are at risk for serious bleeding after delivery. During any pregnancy, the body makes higher amounts of clotting factors to prevent bleeding. However, the high levels of clotting factors during pregnancy drop back to lower levels after delivery. If the woman has low levels of clotting factor, then she can bleed after delivery or surg...

    To reduce the chances of having problems during pregnancy and after delivery, a woman with VWD should: 1. Talk to her doctor about her bleeding disorder before becoming pregnant. 2. Think about seeing a doctor who specializes in high-risk pregnancies and a hospital that has a hematologist (a doctor who specializes in bleeding disorders) on staff fo...

  6. May 1, 2017 · A 37-year-old woman 28 weeks into her first pregnancy is referred to hematology clinic given a history of von Willebrand disease (vWD) diagnosed during her teenage years, after presenting with excessive menstrual bleeding requiring oral iron supplementation.

  7. Nov 30, 2009 · Pregnancy and delivery are considered situations predisposing to a high risk of bleeding in women with von Willebrands disease (VWD). 1, 2 While patients with mild deficiency usually show a spontaneous complete correction of basal low factor VIII (FVIII) and von Willebrand factor (VWF) levels during pregnancy, patients with dysfunctional ...

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