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General guidelines for the treatment of women with von Willebrand disease at delivery. Since pregnant women with VWD are at increased risk of postpartum hemorrhage if untreated 9, 17, 27, 31, treatment options should be planned at the beginning of pregnancy.
- Table 1
Given the wide heterogeneity of phenotypes and of the...
- Mcmdm-1Vwd
Introduction. von Willebrand factor (VWF) is a multimeric...
- Table 1
These test results may be affected by several variables, including stress (eg, surgery, anxiety, or exercise), systemic inflammation or anemia, pregnancy, oral contraceptives, time of the menstrual cycle, sample processing, and the quality of the laboratory 7. Repeat testing may be necessary to establish a definitive diagnosis.
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May 20, 2019 · The variable pattern of changes observed during pregnancy of von Willebrand factor (VWF) and factor VIII (FVIII), the protein carried by VWF, prompts a careful evaluation of pregnant women with VWD to plan the most appropriate treatment at the time of parturition.
- Giancarlo Castaman, Paula D. James
- 2019
Apr 5, 2024 · Von Willebrand Disease (VWD) doctors near me with premium profiles, who have partnered with MediFind to provide additional profile information and enable online scheduling or appointment requests; Von Willebrand Disease (VWD) doctors near me with videos.
- Complete Blood Count
- Activated Partial Thromboplastin Time (APTT) Test
- Prothrombin Time (PT) Test
- Fibrinogen Test
This common test measures the amount of hemoglobin (the red pigment inside red blood cells that carries oxygen), the size and number of red blood cells, and the numbers of different types of white blood cells and platelets found in blood. The CBC is normal among people with VWD. However, if a person with VWD has unusually heavy bleeding or bleeds f...
This test measures how long it takes for blood to clot. It measures the clotting ability of factors VIII (8), IX (9), XI (11), and XII (12). If any of these clotting factors is too low, it will take longer than normal for the blood to clot. The results of this test will show a longer clotting time among some people with VWD. However, the results of...
This test also measures the time it takes for blood to clot. It measures primarily the clotting ability of factors I (1), II (2), V (5), VII (7), and X (10). If the level of any one of these factors is too low, it will take longer than normal for the blood to clot. The results of this test will be normal among most people with VWD.
This test also helps doctors assess a patient’s ability to form a blood clot. This test is ordered either along with other blood clotting tests or when a patient has an abnormal PT or APTT testresult, or both. The results of this test will be normal among people with VWD. Fibrinogen is another name for clotting factor I (1).
Initiation of hormonal therapy, such as oral contraceptive pills or levonorgestrel IUD. Use tranexamic acid, starting on the first day of menses and continuing for 3-5 days with each cycle. Use desmopressin, starting on the first day of menses and given daily for 1-3 days with each cycle. A or B.
Resources. Pregnancy and Delivery for a Woman with Von Willebrand Disease. If you have von Willebrand Disease (VWD), the Indiana Hemophilia and Thrombosis Center (IHTC) can help you have a healthy pregnancy and delivery. Here are some plans to help you get started. Call IHTC Early in Your Pregnancy.
