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  1. Oct 24, 2023 · That study associated vaccination with meningitis, an inflammation of membranes that envelop the brain, and a severe complication of infection known as cerebral malaria. They also found more deaths among girls who received RTS,S than girls who received a comparator vaccine, against rabies.

  2. The pivotal Phase III trial (completed in 2014) showed that the vaccine prevented approximately 4 in 10 (39%) cases of malaria over 4 years and about 3 in 10 (29%) cases of severe malaria among children who received 4 doses of RTS,S. 3 external icon There were also significant reductions in hospital admissions due to malaria.

  3. Jun 18, 2022 · In 2019, children under the age of five accounted for two-thirds of the 409,000 fatalities . In the context of comprehensive malaria control, WHO advises using the RTS, S malaria vaccine to prevent P. falciparum malaria in children residing in WHO-defined moderate to high transmission areas.

  4. Feb 1, 2024 · The two vaccines have not been tested in a head-to-head trial. To date, there is no evidence showing the effects of the vaccines are materially different. Together with prompt diagnosis and treatment, vector control, and chemoprevention, both vaccines will have an important role in malaria control. View Large Image.

  5. Oct 6, 2021 · The World Health Organization (WHO) is recommending widespread use of the RTS,S/AS01 (RTS,S) malaria vaccine among children in sub-Saharan Africa. The recommendation is based on results from an ongoing pilot programme in Ghana, Kenya and Malawi that has reached more than 900 000 children since 2019.

  6. Oct 2, 2023 · In 2021, there were 247 million cases of malaria and 619,000 people died, most of them children under the age of five. More than 95% of malaria is found in Africa. Life-saving potential

  7. Oct 11, 2023 · 11 October 2023. Half a million children die of malaria every year. Finally we can change that. With two vaccines available, this killer disease could now be eliminated — but will the world...