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  2. Dec 14, 2021 · The following chart shows common vaccine side effects based on your age group, vaccine manufacturer, and which dose you received. Data is from each vaccine's clinical trial.

    • Aria Bendix
    • 6 min
  3. May 22, 2022 · The most commonly reported side effects include injection-site pain, fatigue, and headaches. COVID-19 booster shots are now authorized for all individuals in the U.S. who are 5 years and older.

    • Overview
    • Discussion
    • References

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    Table 1

    By August 5, 2022, approximately one half of the eligible population aged ≥5 years had received a COVID-19 vaccine booster dose, representing approximately one third (34.0%) of the U.S. population aged ≥5 years. Booster and second booster dose vaccination coverage rates were lowest among the youngest age groups; males; Black, Hispanic, and multiracial persons; residents of rural counties; and Janssen primary series recipients. Some similarities existed between booster dose coverage and primary series coverage trends as of August 21, 2022, with children, adolescents, younger adults aged 18–24 years, males, and Black persons being underrepresented among fully vaccinated persons (5).

    Booster dose coverage was highest among adults aged ≥65 years (69.5%), with smaller coverage differences across sex, race and ethnicity, and urban-rural classification compared with that in adults aged 18–64 years. Among age groups, the lowest booster dose coverage was among children aged 5–11 years (15.6%), followed by that among adolescents aged 12–17 years (33.4%). Children aged 5–11 years were recommended to receive a booster dose most recently, which might partially explain the low coverage in this group. Racial and ethnic disparities in booster dose coverage were largest (≥26 percentage points) among persons aged 12–39 years. Understanding the factors contributing to low booster and second booster dose coverage among Black, Hispanic, and multiracial populations, and designing interventions to address these factors, is crucial to ensuring equitable access to COVID-19 vaccination.

    Booster and second booster dose coverage rates among Janssen primary series recipients were lower than those among mRNA vaccine recipients. One possible reason for this is the Janssen 1-dose primary series might have been preferred by persons less likely to receive multiple doses, such as transient populations (e.g., persons experiencing homelessness), persons with limited access to health care, and persons with needle aversion. Booster and second booster dose coverage was lower among residents of rural counties than that among urban residents; lower COVID-19 vaccine acceptance has been observed in rural areas, and rural residents might also experience more barriers to accessing health care than do urban residents (6). Persons living in rural areas were previously found to be less likely to engage in COVID-19 preventive behaviors such as mask wearing (7), which would likely increase the potential benefit provided by a booster dose in this population.

    The findings in this report are subject to at least five limitations. First, COVID-19 vaccine booster dose recommendations were released during a 10-month period, and some populations had less time than others to receive a booster dose. Further, changes in COVID-19 variant predominance and case prevalence during this period likely affected booster and second booster dose acceptance among different populations. Second, misclassification of vaccination status might have occurred if linkage among vaccination records in jurisdiction-specific data systems was not possible, if, for example, persons received doses in different jurisdictions. Third, eligibility was determined by age at primary series completion, and a small number of persons who met the minimum eligible age requirement after primary series completion might have been excluded. Fourth, a small proportion of booster and second booster doses might have been misclassified because information on immunocompromise status was not available to identify immunocompromised persons who might have received an additional primary series dose. In addition, misclassification might have occurred due to the definitions for booster and second booster doses, which were designed to include doses administered to immunocompromised persons. However, after receipt of a primary series, approximately 99.0% of persons who received 1 subsequent dose received this dose after the minimum recommended interval for a booster dose; 99.6% of persons who received 2 subsequent doses received the second postprimary series dose after the minimum recommended interval for a second booster dose.§§§ Finally, race or ethnicity was unknown, unable to be reported, or invalid for approximately one quarter of the population, which could bias results. In May 2022, the National Immunization Survey Adult COVID Module (NIS-ACM) found no substantial racial and ethnic disparities among fully vaccinated adults (8); however, disparities across race and ethnicity were present in booster dose coverage based on NIS-ACM.

    1.Accorsi EK, Britton A, Fleming-Dutra KE, et al. Association between 3 doses of mRNA COVID-19 vaccine and symptomatic infection caused by the SARS-CoV-2 Omicron and Delta variants. JAMA 2022;327:639–51. https://doi.org/10.1001/jama.2022.0470 PMID:35060999

    2.Link-Gelles R, Levy ME, Gaglani M, et al. Effectiveness of 2, 3, and 4 COVID-19 mRNA vaccine doses among immunocompetent adults during periods when SARS-CoV-2 Omicron BA.1 and BA.2/BA.2.12.1 sublineages predominated—VISION Network, 10 states, December 2021–June 2022. MMWR Morb Mortal Wkly Rep 2022;71:931–9. https://doi.org/10.15585/mmwr.mm7129e1 PMID:35862287

    3.Fleming-Dutra KE, Britton A, Shang N, et al. Association of prior BNT162b2 COVID-19 vaccination with symptomatic SARS-CoV-2 infection in children and adolescents during Omicron predominance. JAMA 2022;327:2210–9. https://doi.org/10.1001/jama.2022.7493 PMID:35560036

    4.CDC. Interim clinical considerations for use of COVID-19 vaccines currently approved or authorized in the United States. Atlanta, GA: US Department of Health and Human Services, CDC; 2022. https://www.cdc.gov/vaccines/covid-19/clinical-considerations/interim-considerations-us.html

    5.CDC. COVID data tracker. Vaccination delivery and coverage. Atlanta, GA: US Department of Health and Human Services, CDC; 2022. https://covid.cdc.gov/covid-data-tracker/#vaccine-delivery-coverage

    6.Sparks G, Hamel L, Kirzinger A, Stokes M, Brodie M. KFF COVID-19 vaccine monitor: differences in vaccine attitudes between rural, suburban, and urban areas. San Francisco, CA: KFF; 2021. https://www.kff.org/coronavirus-covid-19/poll-finding/kff-covid-19-vaccine-monitor-vaccine-attitudes-rural-suburban-urban/

  4. Jan 6, 2022 · Jan. 6, 2022, at 5:03 p.m. This article is based on reporting that features expert sources. Recommendations for getting the COVID-19 booster vaccine keep getting stronger. Now, everyone ages...

  5. Jun 6, 2022 · Redness and swelling around the injection site. Tiredness. Headache. Muscle and joint pain. Chills. Pfizer also said in a 2021 press release about its EUA application for a booster dose that side ...

  6. Oct 19, 2023 · Similarly to the flu shot, typical side effects of the COVID vaccine include: Headache. Soreness at the site of vaccination. Low fever. Chills. Feeling tired. Is an updated vaccine the same thing as a booster dose? An additional dose is the same as a booster. Does my updated vaccine need to be the same brand as my initial vaccine?

  7. COVID-19 Fact Sheet COVID-19 Vaccine Booster Doses The U.S. Food and Drug Administration (FDA) and Centers for Disease Control and Prevention (CDC) have authorized a booster dose of the Pfizer-BioNTech/Comirnaty COVID-19 vaccine for fully vaccinated people at highest risk for serious outcomes to maximize ongoing protection against COVID-19.

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