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- Mixed results are reported for pregnancy-related nutritional factors and exposure to heavy metals, air pollution, and pesticides, while there is strong evidence that autism risk is unrelated to vaccination, maternal smoking, or thimerosal exposure (Modabbernia et al., 2017).
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Jan 6, 2018 · Autism spectrum disorder has no single known cause. Given the complexity of the disorder, and the fact that symptoms and severity vary, there are probably many causes. Both genetics and environment may play a role. Genetics. Several different genes appear to be involved in autism spectrum disorder.
Aug 20, 2021 · The cause of ASD is unknown, but several genetic and non-genetic risk factors have been characterized that, alone or in combination, are implicated in the development of ASD. Currently, no diagnostic biomarkers are available, and the diagnosis of ASD is based on typical features that include repetitive behaviors, and impaired social ...
- Ann Katrin Sauer, Janelle E. Stanton, Sakshi Hans, Andreas M. Grabrucker
- 2021
Aug 20, 2019 · FIGURE 1. Genetic modifiers in autism spectrum disorder. Autism is estimated to be 40–80% heritable. However, both genetic and non-genetic factors modulate the penetrance of risk genes, resulting in a highly heterogeneous disease phenotype for similar pathogenic variants.
- Lauren Rylaarsdam, Alicia Guemez-Gamboa
- 10.3389/fncel.2019.00385
- 2019
- Front Cell Neurosci. 2019; 13: 385.
Mar 31, 2021 · Genetics, Environment, and More | Psych Central. What Causes Autism Spectrum Disorder? Genetics. Environment. Biology. Risk factors. About vaccines. Diagnosis. Recap. Genetic factors play...
Genetic influences and. Environmental influences, including social determinants. These factors appear to increase the risk of autism and shape the type of autism that a child will develop. However, it’s important to keep in mind that increased risk is not the same as a cause.
Jul 4, 2011 · A new Stanford University School of Medicine study of twins suggests that non-genetic factors play an unexpectedly large role in determining autism risk, turning upside down recent assumptions about the cause of this common, disabling developmental disorder.
Feb 26, 2021 · These and other findings show that the genetic architecture of autism is complex, diverse, and context-dependent, highlighting a need to study the interplay between different types of genetic variants, identify genetic and non-genetic factors influencing their penetrance, and better map the genetic variants to phenotypic heterogeneity within ...
