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  1. What causes autism spectrum disorder? Although the cause of ASD is known in some people and not known in others, genetics, biology, and environment are all important factors. Having older parents, a difficult birth, or infections during pregnancy are all examples of factors that might increase the risk for having ASD. Beyond these factors ...

  2. Scientists don't know exactly what causes autism spectrum disorder (ASD). Autism was first described in the 1940s, but very little was known about it until the last few decades. Even today, there is a great deal that we don't know about autism. Because the disorder is so complex and no two people with autism are exactly alike, there are probably many causes for autism. It is also likely that ...

  3. Feb 26, 2021 · Abstract. Autism spectrum disorder (autism) is a heterogeneous group of neurodevelopmental conditions characterized by early childhood-onset impairments in communication and social interaction alongside restricted and repetitive behaviors and interests. This review summarizes recent developments in human genetics research in autism ...

  4. It has also been known for several decades that single rare medical or genetic conditions are associated with autism. Dozens of genetic syndromes including Joubert Syndrome, Smith Lemli Opitz, Tuberous Sclerosis, and Fragile X are known to cause autism, although many with less than 50% penetrance [ 26, 27 ].

  5. Aug 20, 2021 · Autism spectrum disorders (ASD) are a group of neurodevelopmental diseases. The cause of ASD is unknown, but several genetic and non-genetic risk factors have been characterized that, alone or in combination, are implicated in the development of ASD. Currently, no diagnostic biomarkers are available, and the diagnosis of ASD is based on typical features that include repetitive behaviors, and ...

  6. The conclusion of these recent studies of de novo mutation is that the spectrum of autism is breaking up into quanta of individual disorders defined by genetics. One gene that has been linked to autism is SHANK2. Mutations in this gene act in a dominant fashion. Mutations in this gene appear to cause hyperconnectivity between the neurons.

  7. Dec 9, 2022 · Autism spectrum disorder (ASD) is a developmental disability caused by differences in the brain. Some people with ASD have a known difference, such as a genetic condition. Other causes are not yet known. Scientists believe there are multiple causes of ASD that act together to change the most common ways people develop.

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