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- Sepsis-induced anemia is also known as inflammatory anemia. Tumor necrosis factor (TNF-), interleukin-1 (IL-1) and interleukin-6 (IL-6) induce a reduction in erythropoietin production and an increase in hepcidin, which reduces iron consumption.
www.heartandlung.org › article › S0147-9563(23)00283-2Prognostic value of hemoglobin in patients with sepsis: A ...
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Oct 30, 2007 · Anemia is a common problem in acutely ill patients, especially in those who develop sepsis. There are many factors contributing to the development of anemia in these patients, including blood sampling and other losses, decreased red blood cell (RBC) synthesis, and possibly increased destruction.
- Michaël Piagnerelli, Karim Zouaoui Boudjeltia, Béatrice Gulbis, Michel Vanhaeverbeek, Jean Louis Vin...
- 2007
Dec 8, 2023 · The consequences of sepsis on red blood cells include reduced antioxidant status, changed hemoglobin and oxygen affinity, altered red blood cell size and shape, and altered deformability. Anemia can also be caused by factors such as impaired erythrocyte Ca2+ homeostasis.
Feb 25, 2021 · We here examined the role of virulence and quorum-sensing regulation in mouse and rabbit models of sepsis caused by methicillin-resistant S. aureus (MRSA). We determined that leukopenia was a predictor of disease outcome during an early critical stage of sepsis.
- Gordon Y. C. Cheung, Justin S. Bae, Ryan Liu, Rachelle L. Hunt, Yue Zheng, Michael Otto
- 10.1371/journal.ppat.1009369
- 2021
- PLoS Pathog. 2021 Feb; 17(2): e1009369.
Oct 5, 2020 · In rare instances, patients can develop complications from sepsis; one such complication is autoimmune hemolytic anemia. This patient’s complicated hospital course offers valuable insight on sepsis-induced autoimmune hemolytic anemia. Go to: CASE REPORT.
- Zach Edwards, Stephen DeMeo
- 2020
Jul 27, 2020 · Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease. This broad definition comprises secreted products such as toxins, enzymes, exopolysaccharides, as well as cell surface structures such as capsules, lipopolysaccharides ...
- Jorge H Leitão
- 2020
Feb 10, 2023 · Fast, shallow breathing. Sweating for no clear reason. Feeling lightheaded. Shivering. Symptoms specific to the type of infection, such as painful urination from a urinary tract infection or worsening cough from pneumonia. Symptoms of sepsis are not specific.
Endotoxin triggers humoral enzymatic mechanisms involving the complement, clotting, fibrinolytic, and kinin pathways and causes much of the morbidity in gram-negative bacterial sepsis. Other factors Some microorganisms are more virulent because they do the following:
