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  2. Nov 11, 2022 · Neonatal late-onset sepsis (LOS) remains a significant cause of morbidity and mortality in the NICU, particularly among extremely preterm and/or chronically ill infants.

  3. Nov 1, 2022 · Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

  4. Sep 29, 2022 · Late-onset sepsis (LOS) usually occurs via the transmission of pathogens from the surrounding environment after delivery, such as contact from healthcare workers or caregivers. A percentage ofLOS may also be caused by a late manifestation of vertically transmitted infection.

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29
  5. Late-onset sepsis in premature infants is a major cause of morbidity, mortality, and increased medical costs. Risk factors include low birth weight, low gestational age, previous antimicrobial exposure, poor hand hygiene, and central venous catheters.

    • L. Corbin Downey, P. Brian Smith, Daniel K. Benjamin
    • 10.1016/j.earlhumdev.2010.01.012
    • 2010
    • 2010/07
  6. Nov 11, 2022 · Late-onset sepsis is a significant cause of morbidity and mortality among very preterm infants, leading to high rates of empirical antibiotic administration for suspected infection.

  7. Most cases are caused by group B streptococcus (GBS) and gram-negative enteric organisms (predominantly Escherichia coli). Vaginal or rectal cultures of women at term may show GBS colonization rates of up to 35%. At least 35% of their infants also become colonized.

  8. Feb 24, 2021 · Conclusion. Very preterm infants born after hypertensive disorders or born after FGR had an increased risk of LOS compared to those born after preterm labor. Impact. Late-onset sepsis risk...

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