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      • LOS is primarily attributed to nosocomial or horizontal pathogen acquisition, and exposures to hospital or community environments. Pathogen exposure may occur due to contamination or colonization of indwelling invasive medical devices, contact with care providers, and/or other environmental sources and surfaces.
      www.ncbi.nlm.nih.gov › pmc › articles

      Updates in Late-Onset Sepsis: Risk Assessment, Therapy and ...

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  3. www.ncbi.nlm.nih.gov › pmc › articlesUpdates in Late-Onset Sepsis: Risk Assessment, Therapy and...

    Nov 11, 2022 · Neonatal late-onset sepsis (LOS) remains a significant cause of morbidity and mortality in the NICU, particularly among extremely preterm and/or chronically ill infants. Early recognition and diagnosis of LOS is challenging due to often non-specific presenting features and limited diagnostic efficiency of commonly used biomarkers.

  4. publications.aap.org › neoreviews › articleUpdates in Late-Onset Sepsis: Risk Assessment, Therapy, and ...

    Nov 1, 2022 · Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

  5. www.nature.com › articles › s41390/021/01411-yCause of preterm birth and late-onset sepsis in very preterm ...

    Feb 24, 2021 · 17 Citations. 9 Altmetric. Metrics. Abstract. Background. The pathogenesis of late-onset sepsis (LOS) in preterm infants is poorly understood and knowledge about risk factors,...

    • Mathilde Letouzey, Laurence Foix-L'Hélias, Héloïse Torchin, Ayoub Mitha, Andrei S Morgan, Andrei S M...
    • 2021

  6. publications.aap.org › pediatrics › articleLate-Onset Sepsis Among Very Preterm Infants | Pediatrics ...

    Nov 11, 2022 · Late-onset sepsis is a significant cause of morbidity and mortality among very preterm infants, leading to high rates of empirical antibiotic administration for suspected infection.

  7. www.nature.com › articles › s41372/019/0577-5Standardizing the approach to late onset sepsis in neonates ...

    Jan 6, 2020 · Common indications for LOS evaluations were increased respiratory support (51%) and abdominal distension (17%).

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