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   What is scleroderma & what causes it?

   • Scleroderma is a rare condition that makes your body produce tissue that’s thicker than it should be. Scleroderma usually affects your skin, but can cause symptoms in any tissue throughout your body. Scleroderma is an autoimmune disorder. Autoimmune disorders happen when your immune system accidentally attacks your body instead of protecting it.

   Scleroderma: Symptoms, Causes & Treatment Options - Cleveland Clinic

   my.clevelandclinic.org/health/diseases/scleroderma

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   Who gets scleroderma?

   • Children and seniors get scleroderma. One type, linear morphea, tends to develop before 18 years of age. The other types are most likely to begin between the ages of 30 and 50. Race: Whites and Asians are most likely to get the types of scleroderma that affect only the skin and the tissue that lies beneath.

   Scleroderma: Who gets and causes - American Academy of Dermatology

   www.aad.org/public/diseases/a-z/scleroderma-causes

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   Why does scleroderma make my skin hard?

   • Too much collagen in your skin and other tissues causes areas of tight, hard skin. Scleroderma may involve many systems in your body. There are two major types of scleroderma: Localized scleroderma only affects the skin and the structures directly under the skin.

   What Is Scleroderma? Symptoms & Causes| NIAMS

   www.niams.nih.gov/health-topics/scleroderma

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2. www.mayoclinic.org › diseases-conditions › sclerodermaScleroderma - Symptoms and causes - Mayo Clinic

   www.mayoclinic.org › diseases-conditions › scleroderma

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   Jan 27, 2022 · Causes. Scleroderma results from an overproduction and accumulation of collagen in body tissues. Collagen is a fibrous type of protein that makes up your body's connective tissues, including your skin. Doctors don't know exactly what causes this process to begin, but the body's immune system appears to play a role.

3. my.clevelandclinic.org › health › diseasesScleroderma: Symptoms, Causes & Treatment Options

   my.clevelandclinic.org › health › diseases

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   Sep 29, 2023 · What causes scleroderma? Experts don’t know for sure what causes scleroderma. Some studies have found that it can run in families (meaning biological parents can pass it on to their children), but this is rare enough that there’s no definite proof it’s a genetic disorder .

4. www.niams.nih.gov › health-topics › sclerodermaWhat Is Scleroderma? Symptoms & Causes| NIAMS

   www.niams.nih.gov › health-topics › scleroderma

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   Scleroderma is an autoimmune disease that causes inflammation and fibrosis (thickening) in the skin and other areas of the body. When an immune response tricks tissues into thinking they are injured, it causes inflammation, and the body makes too much collagen, leading to scleroderma.

5. www.webmd.com › sclerodermaScleroderma: Causes, Symptoms, and Treatment - WebMD

   www.webmd.com › scleroderma

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   Feb 27, 2024 · Scleroderma is a long-lasting autoimmune disease that affects your skin, connective tissue, & internal organs. Learn about types, causes, risk factors, symptoms, diagnosis & treatment.

6. www.healthline.com › health › sclerodermaSystemic Sclerosis (Scleroderma): Pictures, Symptoms, Causes

   www.healthline.com › health › scleroderma

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   Feb 8, 2023 · Causes. Risk factors. Symptoms. Pictures. Diagnosis. Complications. Treatment. Outlook. FAQs. Systemic sclerosis (scleroderma) causes the body to destroy healthy tissue. It can change the...

7. www.aad.org › public › diseasesScleroderma: Who gets and causes - American Academy of ...

   www.aad.org › public › diseases

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   What causes scleroderma? Researchers are looking into what actually causes scleroderma. We do know that this group of rare diseases is: NOT contagious. NOT a type of cancer. NOT an infection. We also know that a person develops scleroderma when the body makes too much collagen. This excess collagen is what causes the skin to thicken and harden.

8. www.niams.nih.gov › health-topics › sclerodermaScleroderma Basics: Overview, Symptoms, and Causes

   www.niams.nih.gov › health-topics › scleroderma

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   Scleroderma is an autoimmune disease that causes inflammation and thickening in the skin and other areas of the body. This inflammation leads to areas of tight, hard skin. There are two major types of scleroderma: Localized scleroderma only affects the skin and the structures directly under the skin. Systemic scleroderma, also called systemic ...