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  1. 1 day ago · History. Guest stars have appeared on The Simpsons since its first season, in addition to the show's main cast of Dan Castellaneta, Julie Kavner, Nancy Cartwright, Yeardley Smith, Hank Azaria and Harry Shearer and supporting cast of Tress MacNeille, Pamela Hayden, Maggie Roswell, Chris Edgerly, Dawnn Lewis, Grey DeLisle, Alex Désert, Eric Lopez, Jenny Yokobori, Kimberly D. Brooks, Tony ...