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   How does the IARC select a carcinogenic agent?

   • The IARC staff makes the final selection of agents for review by taking into account the prevalence and intensity of exposure (of both occupational groups and the general population) and availability of sufficient literature for an evaluation of carcinogenicity, as well as advice from the Advisory Groups.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   What are IARC assessments of carcinogenicity based on?

   • IARC assessments of carcinogenicity are based on, and necessarily limited to, scientific evidence available at the time of the review. The evidence comes from epidemiologic studies, animal bioassays, pharmacokinetic/mechanistic experiments, and surveys of human exposure.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   What are IARC monographs used for?

   • IARC Monographs are widely used to identify potential carcinogenic hazards to humans and serve as reference documents summarizing the literature on many different agents.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   Why is identification of carcinogenic hazards important?

   • The identification of carcinogenic hazards is a necessary initial step in cancer prevention. National and international authorities and organizations use information on causes of cancer to support actions to reduce human exposure to carcinogens. More than 1000 agents have been evaluated in the Monographs program.

   The IARC Monographs: Updated Procedures for Modern and Transparent

   www.ncbi.nlm.nih.gov/pmc/articles/PMC6968684/

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2. www.iarc.who.int › infographics › iarc-monographsIARC Monographs hazard classification – IARC

   www.iarc.who.int › infographics › iarc-monographs

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   Jun 16, 2023 · This infographic presents the categories used by the IARC Monographs on the Identification of Carcinogenic Hazards to Humans to classify a substance according to the level of certainty that the substance can cause cancer.

3. monographs.iarc.who.int › home › iarc-monographsIARC Monographs – General Information – IARC Monographs on ...

   monographs.iarc.who.int › home › iarc-monographs

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   The IARC Monographs identify environmental factors that are carcinogenic hazards to humans. These include chemicals, complex mixtures, occupational exposures, physical agents, biological agents, and lifestyle factors.

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5. www.ncbi.nlm.nih.gov › pmc › articlesIARC Monographs: 40 Years of Evaluating Carcinogenic Hazards ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Feb 24, 2015 · Group 2B: The agent is possibly carcinogenic to humans. This category is used for agents for which there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals.

   • Author: Neil Pearce, Aaron Blair, Paolo Vineis, Wolfgang Ahrens, Aage Andersen, Josep M. Anto, Bruce K. Arms...

   • Publish Year: 2015

6. www.ncbi.nlm.nih.gov › pmc › articlesThe IARC Monographs: Updated Procedures for Modern and ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Sep 9, 2019 · The agent is possibly carcinogenic to humans (group 2B): This category generally applies when only one of the following evaluations has been made by the working group: • Limited evidence of carcinogenicity in humans • Sufficient evidence of carcinogenicity in experimental animals

   • Author: Jonathan M Samet, Weihsueh A Chiu, Vincent Cogliano, Jennifer Jinot, David Kriebel, Ruth M Lunn, Fre...

   • Publish Year: 2020

7. www.cancer.org › cancer › risk-preventionDetermining if Something Is a Carcinogen | American Cancer ...

   www.cancer.org › cancer › risk-prevention

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   What is a carcinogen? Substances and exposures that can lead to cancer are called carcinogens. In general, the American Cancer Society does not determine if something causes cancer (that is, if it is a carcinogen ), but we do look to other respected organizations for help with this.

8. canceratlas.cancer.org › human-carcinogensHuman Carcinogens | The Cancer Atlas

   canceratlas.cancer.org › human-carcinogens

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   Human immunodeficiency virus type 1 (HIV) Ultraviolet-emitting tanning devices. Welding. Oral Cavity and Pharynx. ORAL CAVITY. Alcoholic beverages. Betel quid with tobacco. Betel quid without tobacco. Human papillomavirus type 16. Smokeless tobacco. Tobacco smoking. PHARYNX (ORO-, HYPO- AND/OR NOT OTHERWISE SPECIFIED) Alcoholic beverages.

9. monographs.iarc.who.intIARC Monographs on the Identification of Carcinogenic Hazards ...

   monographs.iarc.who.int

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   IARC Monographs on the Identification of Carcinogenic Hazards to Humans – INTERNATIONAL AGENCY FOR RESEARCH ON CANCER. General Information.